GO ID:0007242
Term :intracellular signaling cascade

Entrez Gene IDs are linked to their corresponding NCBI GenBank entry. Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database. Note that a login is required for the HD Research CrossRoads database.

Entrez Gene IDApproved SymbolApproved Name
16AARSalanyl-tRNA synthetase
107ADCY1adenylate cyclase 1 (brain)
135ADORA2Aadenosine A2a receptor
207AKT1v-akt murine thymoma viral oncogene homolog 1
348APOEapolipoprotein E
378ARF4ADP-ribosylation factor 4
701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)
834CASP1caspase 1, apoptosis-related cysteine peptidase
847CATcatalase
857CAV1caveolin 1, caveolae protein, 22kDa
1012CDH13cadherin 13, H-cadherin (heart)
1020CDK5cyclin-dependent kinase 5
1072CFL1cofilin 1 (non-muscle)
1147CHUKconserved helix-loop-helix ubiquitous kinase
1268CNR1cannabinoid receptor 1 (brain)
1269CNR2cannabinoid receptor 2 (macrophage)
1270CNTFciliary neurotrophic factor
1499CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1827RCAN1regulator of calcineurin 1
1950EGFepidermal growth factor
2247FGF2fibroblast growth factor 2 (basic)
2357FPR1formyl peptide receptor 1
2475MTORmechanistic target of rapamycin (serine/threonine kinase)
2740GLP1Rglucagon-like peptide 1 receptor
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
2810SFNstratifin
2904GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B
2915GRM5glutamate receptor, metabotropic 5
2932GSK3Bglycogen synthase kinase 3 beta
3148HMGB2high mobility group box 2
3301DNAJA1DnaJ (Hsp40) homolog, subfamily A, member 1
3309HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
3355HTR1F5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
3362HTR65-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
3479IGF1insulin-like growth factor 1 (somatomedin C)
3654IRAK1interleukin-1 receptor-associated kinase 1
4214MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
4217MAP3K5mitogen-activated protein kinase kinase kinase 5
4293MAP3K9mitogen-activated protein kinase kinase kinase 9
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4296MAP3K11mitogen-activated protein kinase kinase kinase 11
4436MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
4803NGFnerve growth factor (beta polypeptide)
4852NPYneuropeptide Y
4902NRTNneurturin
5027P2RX7purinergic receptor P2X, ligand-gated ion channel, 7
5058PAK1p21 protein (Cdc42/Rac)-activated kinase 1
5286PIK3C2Aphosphoinositide-3-kinase, class 2, alpha polypeptide
5289PIK3C3phosphoinositide-3-kinase, class 3
5290PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide
5291PIK3CBphosphoinositide-3-kinase, catalytic, beta polypeptide
5566PRKACAprotein kinase, cAMP-dependent, catalytic, alpha
5579PRKCBprotein kinase C, beta
5599MAPK8mitogen-activated protein kinase 8
5601MAPK9mitogen-activated protein kinase 9
5602MAPK10mitogen-activated protein kinase 10
5604MAP2K1mitogen-activated protein kinase kinase 1
5606MAP2K3mitogen-activated protein kinase kinase 3
5608MAP2K6mitogen-activated protein kinase kinase 6
5728PTENphosphatase and tensin homolog
5861RAB1ARAB1A, member RAS oncogene family
5868RAB5ARAB5A, member RAS oncogene family
5901RANRAN, member RAS oncogene family
5912RAP2BRAP2B, member of RAS oncogene family
6009RHEBRas homolog enriched in brain
6093ROCK1Rho-associated, coiled-coil containing protein kinase 1
6199RPS6KB2ribosomal protein S6 kinase, 70kDa, polypeptide 2
6416MAP2K4mitogen-activated protein kinase kinase 4
6453ITSN1intersectin 1 (SH3 domain protein)
6647SOD1superoxide dismutase 1, soluble
7052TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
7157TP53tumor protein p53
7161TP73tumor protein p73
7188TRAF5TNF receptor-associated factor 5
7204TRIOtriple functional domain (PTPRF interacting)
7248TSC1tuberous sclerosis 1
7249TSC2tuberous sclerosis 2
7334UBE2Nubiquitin-conjugating enzyme E2N
7415VCPvalosin containing protein
7531YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
8408ULK1unc-51-like kinase 1 (C. elegans)
8517IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
8729GBF1golgi brefeldin A resistant guanine nucleotide exchange factor 1
8766RAB11ARAB11A, member RAS oncogene family
8767RIPK2receptor-interacting serine-threonine kinase 2
8878SQSTM1sequestosome 1
9230RAB11BRAB11B, member RAS oncogene family
9252RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
9459ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
9475ROCK2Rho-associated, coiled-coil containing protein kinase 2
9479MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1
9886RHOBTB1Rho-related BTB domain containing 1
9908G3BP2GTPase activating protein (SH3 domain) binding protein 2
9927MFN2mitofusin 2
10125RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated)
10342TFGTRK-fused gene
10411RAPGEF3Rap guanine nucleotide exchange factor (GEF) 3
10891PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha
11188NISCHnischarin
22858ICKintestinal cell (MAK-like) kinase
23390ZDHHC17zinc finger, DHHC-type containing 17
23411SIRT1sirtuin 1
23551RASD2RASD family, member 2
23604DAPK2death-associated protein kinase 2
23636NUP62nucleoporin 62kDa
50618ITSN2intersectin 2
51196PLCE1phospholipase C, epsilon 1
51701NLKnemo-like kinase
54503ZDHHC13zinc finger, DHHC-type containing 13
55647RAB20RAB20, member RAS oncogene family
55803ADAP2ArfGAP with dual PH domains 2
133522PPARGC1Bperoxisome proliferator-activated receptor gamma, coactivator 1 beta