GO ID:0009056
Term :catabolic process

Entrez Gene IDs are linked to their corresponding NCBI GenBank entry. Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database. Note that a login is required for the HD Research CrossRoads database.

Entrez Gene IDApproved SymbolApproved Name
207AKT1v-akt murine thymoma viral oncogene homolog 1
208AKT2v-akt murine thymoma viral oncogene homolog 2
226ALDOAaldolase A, fructose-bisphosphate
331XIAPX-linked inhibitor of apoptosis
348APOEapolipoprotein E
513ATP5DATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)
726CAPN5calpain 5
823CAPN1calpain 1, (mu/I) large subunit
824CAPN2calpain 2, (m/II) large subunit
834CASP1caspase 1, apoptosis-related cysteine peptidase
835CASP2caspase 2, apoptosis-related cysteine peptidase
836CASP3caspase 3, apoptosis-related cysteine peptidase
839CASP6caspase 6, apoptosis-related cysteine peptidase
840CASP7caspase 7, apoptosis-related cysteine peptidase
847CATcatalase
891CCNB1cyclin B1
1020CDK5cyclin-dependent kinase 5
1374CPT1Acarnitine palmitoyltransferase 1A (liver)
1431CScitrate synthase
1509CTSDcathepsin D
1514CTSL1cathepsin L1
1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 1
2071ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3
2073ERCC5excision repair cross-complementing rodent repair deficiency, complementation group 5
2184FAHfumarylacetoacetate hydrolase (fumarylacetoacetase)
2475MTORmechanistic target of rapamycin (serine/threonine kinase)
2597GAPDHglyceraldehyde-3-phosphate dehydrogenase
2805GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
2819GPD1glycerol-3-phosphate dehydrogenase 1 (soluble)
2821GPIglucose-6-phosphate isomerase
2935GSPT1G1 to S phase transition 1
3066HDAC2histone deacetylase 2
3093UBE2Kubiquitin-conjugating enzyme E2K
3479IGF1insulin-like growth factor 1 (somatomedin C)
3646EIF3Eeukaryotic translation initiation factor 3, subunit E
3818KLKB1kallikrein B, plasma (Fletcher factor) 1
4023LPLlipoprotein lipase
4319MMP10matrix metallopeptidase 10 (stromelysin 2)
4323MMP14matrix metallopeptidase 14 (membrane-inserted)
4842NOS1nitric oxide synthase 1 (neuronal)
4905NSFN-ethylmaleimide-sensitive factor
4968OGG18-oxoguanine DNA glycosylase
5071PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
5160PDHA1pyruvate dehydrogenase (lipoamide) alpha 1
5213PFKMphosphofructokinase, muscle
5230PGK1phosphoglycerate kinase 1
5315PKM2pyruvate kinase, muscle
5655KLK10kallikrein-related peptidase 10
5682PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
5686PSMA5proteasome (prosome, macropain) subunit, alpha type, 5
5688PSMA7proteasome (prosome, macropain) subunit, alpha type, 7
5690PSMB2proteasome (prosome, macropain) subunit, beta type, 2
5691PSMB3proteasome (prosome, macropain) subunit, beta type, 3
5693PSMB5proteasome (prosome, macropain) subunit, beta type, 5
5694PSMB6proteasome (prosome, macropain) subunit, beta type, 6
5695PSMB7proteasome (prosome, macropain) subunit, beta type, 7
5701PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 2
5702PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 3
5705PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 5
5706PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 6
5708PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
5709PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
5710PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
5713PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
5714PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
5717PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
5903RANBP2RAN binding protein 2
5976UPF1UPF1 regulator of nonsense transcripts homolog (yeast)
6389SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)
6390SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)
6477SIAH1siah E3 ubiquitin protein ligase 1
6500SKP1S-phase kinase-associated protein 1
6531SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
6612SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
6647SOD1superoxide dismutase 1, soluble
7078TIMP3TIMP metallopeptidase inhibitor 3
7251TSG101tumor susceptibility gene 101
7314UBBubiquitin B
7317UBA1ubiquitin-like modifier activating enzyme 1
7319UBE2Aubiquitin-conjugating enzyme E2A
7322UBE2D2ubiquitin-conjugating enzyme E2D 2
7323UBE2D3ubiquitin-conjugating enzyme E2D 3
7328UBE2Hubiquitin-conjugating enzyme E2H
7329UBE2Iubiquitin-conjugating enzyme E2I
7334UBE2Nubiquitin-conjugating enzyme E2N
7336UBE2V2ubiquitin-conjugating enzyme E2 variant 2
7337UBE3Aubiquitin protein ligase E3A
7341SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
7345UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
7347UCHL3ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
7353UFD1Lubiquitin fusion degradation 1 like (yeast)
7415VCPvalosin containing protein
8239USP9Xubiquitin specific peptidase 9, X-linked
8288EPXeosinophil peroxidase
8408ULK1unc-51-like kinase 1 (C. elegans)
8453CUL2cullin 2
8454CUL1cullin 1
8510MMP23Bmatrix metallopeptidase 23B
8622PDE8Bphosphodiesterase 8B
8660IRS2insulin receptor substrate 2
8678BECN1beclin 1, autophagy related
8878SQSTM1sequestosome 1
8945BTRCbeta-transducin repeat containing E3 ubiquitin protein ligase
9184BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)
9474ATG5autophagy related 5
9525VPS4Bvacuolar protein sorting 4 homolog B (S. cerevisiae)
9730VPRBPVpr (HIV-1) binding protein
10054UBA2ubiquitin-like modifier activating enzyme 2
10055SAE1SUMO1 activating enzyme subunit 1
10197PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
10213PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
10273STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
10533ATG7autophagy related 7
10939AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
11012KLK11kallikrein-related peptidase 11
23049SMG1smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
23077MYCBP2MYC binding protein 2, E3 ubiquitin protein ligase
23381SMG5smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
25825BACE2beta-site APP-cleaving enzyme 2
26019UPF2UPF2 regulator of nonsense transcripts homolog (yeast)
26260FBXO25F-box protein 25
27429HTRA2HtrA serine peptidase 2
28972SPCS1signal peptidase complex subunit 1 homolog (S. cerevisiae)
50506DUOX2dual oxidase 2
51196PLCE1phospholipase C, epsilon 1
51343FZR1fizzy/cell division cycle 20 related 1 (Drosophila)
55666NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)
59343SENP2SUMO1/sentrin/SMT3 specific peptidase 2
64699TMPRSS3transmembrane protease, serine 3
84447SYVN1synovial apoptosis inhibitor 1, synoviolin
114769CARD16caspase recruitment domain family, member 16
115426UHRF2ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase