GO ID:0043283
Term :biopolymer metabolic process

Entrez Gene IDs are linked to their corresponding NCBI GenBank entry. Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database. Note that a login is required for the HD Research CrossRoads database.

Entrez Gene IDApproved SymbolApproved Name
16AARSalanyl-tRNA synthetase
118ADD1adducin 1 (alpha)
207AKT1v-akt murine thymoma viral oncogene homolog 1
208AKT2v-akt murine thymoma viral oncogene homolog 2
331XIAPX-linked inhibitor of apoptosis
348APOEapolipoprotein E
444ASPHaspartate beta-hydroxylase
467ATF3activating transcription factor 3
538ATP7AATPase, Cu++ transporting, alpha polypeptide
596BCL2B-cell CLL/lymphoma 2
701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)
726CAPN5calpain 5
823CAPN1calpain 1, (mu/I) large subunit
824CAPN2calpain 2, (m/II) large subunit
834CASP1caspase 1, apoptosis-related cysteine peptidase
835CASP2caspase 2, apoptosis-related cysteine peptidase
836CASP3caspase 3, apoptosis-related cysteine peptidase
839CASP6caspase 6, apoptosis-related cysteine peptidase
840CASP7caspase 7, apoptosis-related cysteine peptidase
847CATcatalase
891CCNB1cyclin B1
908CCT6Achaperonin containing TCP1, subunit 6A (zeta 1)
988CDC5LCDC5 cell division cycle 5-like (S. pombe)
1020CDK5cyclin-dependent kinase 5
1072CFL1cofilin 1 (non-muscle)
1147CHUKconserved helix-loop-helix ubiquitous kinase
1270CNTFciliary neurotrophic factor
1385CREB1cAMP responsive element binding protein 1
1387CREBBPCREB binding protein
1410CRYABcrystallin, alpha B
1457CSNK2A1casein kinase 2, alpha 1 polypeptide
1499CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa
1509CTSDcathepsin D
1514CTSL1cathepsin L1
1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 1
1659DHX8DEAH (Asp-Glu-Ala-His) box polypeptide 8
1785DNM2dynamin 2
1849DUSP7dual specificity phosphatase 7
1917EEF1A2eukaryotic translation elongation factor 1 alpha 2
1938EEF2eukaryotic translation elongation factor 2
1950EGFepidermal growth factor
1968EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
1983EIF5eukaryotic translation initiation factor 5
2019EN1engrailed homeobox 1
2071ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3
2073ERCC5excision repair cross-complementing rodent repair deficiency, complementation group 5
2107ETF1eukaryotic translation termination factor 1
2247FGF2fibroblast growth factor 2 (basic)
2309FOXO3forkhead box O3
2339FNTAfarnesyltransferase, CAAX box, alpha
2342FNTBfarnesyltransferase, CAAX box, beta
2357FPR1formyl peptide receptor 1
2444FRKfyn-related kinase
2475MTORmechanistic target of rapamycin (serine/threonine kinase)
2547XRCC6X-ray repair complementing defective repair in Chinese hamster cells 6
2648KAT2AK(lysine) acetyltransferase 2A
2668GDNFglial cell derived neurotrophic factor
2891GRIA2glutamate receptor, ionotropic, AMPA 2
2902GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
2909GRLF1Rho GTPase activating protein 35
2932GSK3Bglycogen synthase kinase 3 beta
2935GSPT1G1 to S phase transition 1
3065HDAC1histone deacetylase 1
3066HDAC2histone deacetylase 2
3084NRG1neuregulin 1
3092HIP1huntingtin interacting protein 1
3093UBE2Kubiquitin-conjugating enzyme E2K
3146HMGB1high mobility group box 1
3148HMGB2high mobility group box 2
3178HNRNPA1heterogeneous nuclear ribonucleoprotein A1
3297HSF1heat shock transcription factor 1
3300DNAJB2DnaJ (Hsp40) homolog, subfamily B, member 2
3301DNAJA1DnaJ (Hsp40) homolog, subfamily A, member 1
3312HSPA8heat shock 70kDa protein 8
3313HSPA9heat shock 70kDa protein 9 (mortalin)
3315HSPB1heat shock 27kDa protein 1
3320HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 1
3337DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 1
3479IGF1insulin-like growth factor 1 (somatomedin C)
3551IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
3646EIF3Eeukaryotic translation initiation factor 3, subunit E
3654IRAK1interleukin-1 receptor-associated kinase 1
3725JUNjun proto-oncogene
3727JUNDjun D proto-oncogene
3818KLKB1kallikrein B, plasma (Fletcher factor) 1
3921RPSAribosomal protein SA
4205MEF2Amyocyte enhancer factor 2A
4214MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
4217MAP3K5mitogen-activated protein kinase kinase kinase 5
4255MGMTO-6-methylguanine-DNA methyltransferase
4291MLF1myeloid leukemia factor 1
4293MAP3K9mitogen-activated protein kinase kinase kinase 9
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4296MAP3K11mitogen-activated protein kinase kinase kinase 11
4319MMP10matrix metallopeptidase 10 (stromelysin 2)
4323MMP14matrix metallopeptidase 14 (membrane-inserted)
4436MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
4437MSH3mutS homolog 3 (E. coli)
4521NUDT1nudix (nucleoside diphosphate linked moiety X)-type motif 1
4773NFATC2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
4803NGFnerve growth factor (beta polypeptide)
4809NHP2L1NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
4905NSFN-ethylmaleimide-sensitive factor
4928NUP98nucleoporin 98kDa
4968OGG18-oxoguanine DNA glycosylase
5058PAK1p21 protein (Cdc42/Rac)-activated kinase 1
5062PAK2p21 protein (Cdc42/Rac)-activated kinase 2
5071PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
5190PEX6peroxisomal biogenesis factor 6
5216PFN1profilin 1
5217PFN2profilin 2
5289PIK3C3phosphoinositide-3-kinase, class 3
5290PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide
5291PIK3CBphosphoinositide-3-kinase, catalytic, beta polypeptide
5300PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 1
5347PLK1polo-like kinase 1
5356PLRG1pleiotropic regulator 1
5430POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa
5431POLR2Bpolymerase (RNA) II (DNA directed) polypeptide B, 140kDa
5468PPARGperoxisome proliferator-activated receptor gamma
5495PPM1Bprotein phosphatase, Mg2+/Mn2+ dependent, 1B
5530PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme
5557PRIM1primase, DNA, polypeptide 1 (49kDa)
5566PRKACAprotein kinase, cAMP-dependent, catalytic, alpha
5579PRKCBprotein kinase C, beta
5586PKN2protein kinase N2
5599MAPK8mitogen-activated protein kinase 8
5601MAPK9mitogen-activated protein kinase 9
5602MAPK10mitogen-activated protein kinase 10
5604MAP2K1mitogen-activated protein kinase kinase 1
5606MAP2K3mitogen-activated protein kinase kinase 3
5608MAP2K6mitogen-activated protein kinase kinase 6
5655KLK10kallikrein-related peptidase 10
5682PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
5686PSMA5proteasome (prosome, macropain) subunit, alpha type, 5
5688PSMA7proteasome (prosome, macropain) subunit, alpha type, 7
5690PSMB2proteasome (prosome, macropain) subunit, beta type, 2
5691PSMB3proteasome (prosome, macropain) subunit, beta type, 3
5693PSMB5proteasome (prosome, macropain) subunit, beta type, 5
5694PSMB6proteasome (prosome, macropain) subunit, beta type, 6
5695PSMB7proteasome (prosome, macropain) subunit, beta type, 7
5701PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 2
5702PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 3
5705PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 5
5706PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 6
5708PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
5709PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
5710PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
5713PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
5714PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
5717PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
5727PTCH1patched 1
5728PTENphosphatase and tensin homolog
5901RANRAN, member RAS oncogene family
5903RANBP2RAN binding protein 2
5976UPF1UPF1 regulator of nonsense transcripts homolog (yeast)
5978RESTRE1-silencing transcription factor
6093ROCK1Rho-associated, coiled-coil containing protein kinase 1
6096RORBRAR-related orphan receptor B
6125RPL5ribosomal protein L5
6128RPL6ribosomal protein L6
6129RPL7ribosomal protein L7
6130RPL7Aribosomal protein L7a
6132RPL8ribosomal protein L8
6137RPL13ribosomal protein L13
6138RPL15ribosomal protein L15
6139RPL17ribosomal protein L17
6141RPL18ribosomal protein L18
6142RPL18Aribosomal protein L18a
6143RPL19ribosomal protein L19
6146RPL22ribosomal protein L22
6152RPL24ribosomal protein L24
6154RPL26ribosomal protein L26
6160RPL31ribosomal protein L31
6170RPL39ribosomal protein L39
6175RPLP0ribosomal protein, large, P0
6187RPS2ribosomal protein S2
6188RPS3ribosomal protein S3
6189RPS3Aribosomal protein S3A
6193RPS5ribosomal protein S5
6199RPS6KB2ribosomal protein S6 kinase, 70kDa, polypeptide 2
6204RPS10ribosomal protein S10
6206RPS12ribosomal protein S12
6209RPS15ribosomal protein S15
6217RPS16ribosomal protein S16
6222RPS18ribosomal protein S18
6227RPS21ribosomal protein S21
6311ATXN2ataxin 2
6416MAP2K4mitogen-activated protein kinase kinase 4
6477SIAH1siah E3 ubiquitin protein ligase 1
6500SKP1S-phase kinase-associated protein 1
6597SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
6601SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
6612SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
6628SNRPBsmall nuclear ribonucleoprotein polypeptides B and B1
6632SNRPD1small nuclear ribonucleoprotein D1 polypeptide 16kDa
6633SNRPD2small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
6634SNRPD3small nuclear ribonucleoprotein D3 polypeptide 18kDa
6636SNRPFsmall nuclear ribonucleoprotein polypeptide F
6637SNRPGsmall nuclear ribonucleoprotein polypeptide G
6647SOD1superoxide dismutase 1, soluble
6667SP1Sp1 transcription factor
6720SREBF1sterol regulatory element binding transcription factor 1
6721SREBF2sterol regulatory element binding transcription factor 2
6749SSRP1structure specific recognition protein 1
6829SUPT5Hsuppressor of Ty 5 homolog (S. cerevisiae)
6874TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
6875TAF4BTAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
6950TCP1t-complex 1
7029TFDP2transcription factor Dp-2 (E2F dimerization partner 2)
7052TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
7078TIMP3TIMP metallopeptidase inhibitor 3
7157TP53tumor protein p53
7161TP73tumor protein p73
7204TRIOtriple functional domain (PTPRF interacting)
7248TSC1tuberous sclerosis 1
7251TSG101tumor susceptibility gene 101
7266DNAJC7DnaJ (Hsp40) homolog, subfamily C, member 7
7307U2AF1U2 small nuclear RNA auxiliary factor 1
7314UBBubiquitin B
7317UBA1ubiquitin-like modifier activating enzyme 1
7319UBE2Aubiquitin-conjugating enzyme E2A
7322UBE2D2ubiquitin-conjugating enzyme E2D 2
7323UBE2D3ubiquitin-conjugating enzyme E2D 3
7328UBE2Hubiquitin-conjugating enzyme E2H
7329UBE2Iubiquitin-conjugating enzyme E2I
7334UBE2Nubiquitin-conjugating enzyme E2N
7336UBE2V2ubiquitin-conjugating enzyme E2 variant 2
7337UBE3Aubiquitin protein ligase E3A
7341SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
7345UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
7347UCHL3ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
7353UFD1Lubiquitin fusion degradation 1 like (yeast)
7376NR1H2nuclear receptor subfamily 1, group H, member 2
7415VCPvalosin containing protein
7469WHSC2Wolf-Hirschhorn syndrome candidate 2
7531YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
7637ZNF84zinc finger protein 84
7919BAT1DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
7936RDBPRD RNA binding protein
7942TFEBtranscription factor EB
8091HMGA2high mobility group AT-hook 2
8239USP9Xubiquitin specific peptidase 9, X-linked
8295TRRAPtransformation/transcription domain-associated protein
8408ULK1unc-51-like kinase 1 (C. elegans)
8453CUL2cullin 2
8454CUL1cullin 1
8510MMP23Bmatrix metallopeptidase 23B
8517IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
8568RRP1ribosomal RNA processing 1 homolog (S. cerevisiae)
8622PDE8Bphosphodiesterase 8B
8660IRS2insulin receptor substrate 2
8661EIF3Aeukaryotic translation initiation factor 3, subunit A
8662EIF3Beukaryotic translation initiation factor 3, subunit B
8668EIF3Ieukaryotic translation initiation factor 3, subunit I
8721EDF1endothelial differentiation-related factor 1
8767RIPK2receptor-interacting serine-threonine kinase 2
8841HDAC3histone deacetylase 3
8878SQSTM1sequestosome 1
8894EIF2S2eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
8898MTMR2myotubularin related protein 2
8945BTRCbeta-transducin repeat containing E3 ubiquitin protein ligase
9045RPL14ribosomal protein L14
9126SMC3structural maintenance of chromosomes 3
9184BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)
9252RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
9343EFTUD2elongation factor Tu GTP binding domain containing 2
9349RPL23ribosomal protein L23
9439MED23mediator complex subunit 23
9474ATG5autophagy related 5
9475ROCK2Rho-associated, coiled-coil containing protein kinase 2
9531BAG3BCL2-associated athanogene 3
9572NR1D1nuclear receptor subfamily 1, group D, member 1
9611NCOR1nuclear receptor corepressor 1
9689BZW1basic leucine zipper and W2 domains 1
9730VPRBPVpr (HIV-1) binding protein
9734HDAC9histone deacetylase 9
9759HDAC4histone deacetylase 4
10013HDAC6histone deacetylase 6
10049DNAJB6DnaJ (Hsp40) homolog, subfamily B, member 6
10054UBA2ubiquitin-like modifier activating enzyme 2
10055SAE1SUMO1 activating enzyme subunit 1
10056FARSBphenylalanyl-tRNA synthetase, beta subunit
10062NR1H3nuclear receptor subfamily 1, group H, member 3
10109ARPC2actin related protein 2/3 complex, subunit 2, 34kDa
10113PREBprolactin regulatory element binding
10197PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
10212DDX39DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
10213PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
10262SF3B4splicing factor 3b, subunit 4, 49kDa
10273STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
10294DNAJA2DnaJ (Hsp40) homolog, subfamily A, member 2
10411RAPGEF3Rap guanine nucleotide exchange factor (GEF) 3
10533ATG7autophagy related 7
10569SLU7SLU7 splicing factor homolog (S. cerevisiae)
10574CCT7chaperonin containing TCP1, subunit 7 (eta)
10575CCT4chaperonin containing TCP1, subunit 4 (delta)
10576CCT2chaperonin containing TCP1, subunit 2 (beta)
10594PRPF8PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
10891PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha
10915TCERG1transcription elongation regulator 1
10939AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
10946SF3A3splicing factor 3a, subunit 3, 60kDa
10992SF3B2splicing factor 3b, subunit 2, 145kDa
11012KLK11kallikrein-related peptidase 11
11030RBPMSRNA binding protein with multiple splicing
11080DNAJB4DnaJ (Hsp40) homolog, subfamily B, member 4
11198SUPT16Hsuppressor of Ty 16 homolog (S. cerevisiae)
11224RPL35ribosomal protein L35
22858ICKintestinal cell (MAK-like) kinase
22929SEPHS1selenophosphate synthetase 1
22933SIRT2sirtuin 2
22938SNW1SNW domain containing 1
22948CCT5chaperonin containing TCP1, subunit 5 (epsilon)
23019CNOT1CCR4-NOT transcription complex, subunit 1
23020SNRNP200small nuclear ribonucleoprotein 200kDa (U5)
23049SMG1smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
23077MYCBP2MYC binding protein 2, E3 ubiquitin protein ligase
23090ZNF423zinc finger protein 423
23144ZC3H3zinc finger CCCH-type containing 3
23369PUM2pumilio homolog 2 (Drosophila)
23381SMG5smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
23389MED13Lmediator complex subunit 13-like
23390ZDHHC17zinc finger, DHHC-type containing 17
23409SIRT4sirtuin 4
23411SIRT1sirtuin 1
23450SF3B3splicing factor 3b, subunit 3, 130kDa
23451SF3B1splicing factor 3b, subunit 1, 155kDa
23481PES1pescadillo ribosomal biogenesis factor 1
23517SKIV2L2superkiller viralicidic activity 2-like 2 (S. cerevisiae)
23560GTPBP4GTP binding protein 4
23604DAPK2death-associated protein kinase 2
23636NUP62nucleoporin 62kDa
25788RAD54BRAD54 homolog B (S. cerevisiae)
25825BACE2beta-site APP-cleaving enzyme 2
25896INTS7integrator complex subunit 7
25920COBRA1cofactor of BRCA1
25942SIN3ASIN3 transcription regulator homolog A (yeast)
26019UPF2UPF2 regulator of nonsense transcripts homolog (yeast)
26121PRPF31PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
26173INTS1integrator complex subunit 1
26260FBXO25F-box protein 25
26750RPS6KC1ribosomal protein S6 kinase, 52kDa, polypeptide 1
27161EIF2C2eukaryotic translation initiation factor 2C, 2
27339PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
27429HTRA2HtrA serine peptidase 2
28972SPCS1signal peptidase complex subunit 1 homolog (S. cerevisiae)
29959NRBP1nuclear receptor binding protein 1
51160VPS28vacuolar protein sorting 28 homolog (S. cerevisiae)
51176LEF1lymphoid enhancer-binding factor 1
51196PLCE1phospholipase C, epsilon 1
51340CRNKL1crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
51343FZR1fizzy/cell division cycle 20 related 1 (Drosophila)
51497TH1LTH1-like (Drosophila)
51616TAF9BTAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
51692CPSF3cleavage and polyadenylation specific factor 3, 73kDa
51701NLKnemo-like kinase
53981CPSF2cleavage and polyadenylation specific factor 2, 100kDa
54039PCBP3poly(rC) binding protein 3
54583EGLN1egl nine homolog 1 (C. elegans)
54623PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
55339WDR33WD repeat domain 33
55589BMP2KBMP2 inducible kinase
55656INTS8integrator complex subunit 8
55666NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)
55756INTS9integrator complex subunit 9
56033BARX1BARX homeobox 1
56949XAB2XPA binding protein 2
57461ISY1ISY1 splicing factor homolog (S. cerevisiae)
57508INTS2integrator complex subunit 2
57551TAOK1TAO kinase 1
58509C19orf29cactin, spliceosome C complex subunit
59343SENP2SUMO1/sentrin/SMT3 specific peptidase 2
60559SPCS3signal peptidase complex subunit 3 homolog (S. cerevisiae)
64699TMPRSS3transmembrane protease, serine 3
80789INTS5integrator complex subunit 5
84313VPS25vacuolar protein sorting 25 homolog (S. cerevisiae)
84447SYVN1synovial apoptosis inhibitor 1, synoviolin
92105INTS4integrator complex subunit 4
114769CARD16caspase recruitment domain family, member 16
115426UHRF2ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
133522PPARGC1Bperoxisome proliferator-activated receptor gamma, coactivator 1 beta
140890SFRS12splicing regulatory glutamine/lysine-rich protein 1
149076ZNF362zinc finger protein 362
266743NPAS4neuronal PAS domain protein 4
284086NEK8NIMA (never in mitosis gene a)- related kinase 8
100129885SCXAscleraxis homolog A (mouse)