Cellular Components enriched in HD-relevant genes

GO IDs are linked to the Gene Ontology website (www.geneontology.org). The list of HD-relevant genes for each category can be found following the links provided in the Term column.

GOBPID P-Value FDR Odds Ratio Expected Count Count Total number Term
GO:0005829 8.87E-58 4.38E-55 5.78 41.95 167 1039 cytosol
GO:0032991 2.95E-56 7.28E-54 4.06 100.21 263 2482 macromolecular complex
GO:0005737 3.66E-38 6.02E-36 2.89 280.45 440 6946 cytoplasm
GO:0005622 6.63E-35 8.19E-33 3.56 429.85 564 10646 intracellular
GO:0044424 1.45E-34 1.43E-32 3.36 413.86 551 10250 intracellular part
GO:0043234 2.33E-34 1.92E-32 3.28 78.45 192 1943 protein complex
GO:0044446 4.97E-32 3.51E-30 2.68 153.63 287 3805 intracellular organelle part
GO:0044422 1.59E-31 9.82E-30 2.66 154.60 287 3829 organelle part
GO:0044444 1.33E-29 7.30E-28 2.53 179.63 312 4449 cytoplasmic part
GO:0044445 3.36E-26 1.66E-24 10.98 5.73 43 142 cytosolic part
GO:0044428 1.03E-25 4.62E-24 2.97 67.22 158 1665 nuclear part
GO:0030529 9.47E-24 3.90E-22 4.81 18.93 73 469 ribonucleoprotein complex
GO:0005654 3.16E-20 1.20E-18 3.49 31.09 90 770 nucleoplasm
GO:0022626 6.42E-20 2.27E-18 14.15 3.10 28 77 cytosolic ribosome
GO:0043229 1.39E-19 4.54E-18 2.14 349.05 459 8645 intracellular organelle
GO:0043226 1.47E-19 4.54E-18 2.14 349.13 459 8647 organelle
GO:0031981 1.78E-19 5.17E-18 2.79 54.06 125 1339 nuclear lumen
GO:0031974 5.00E-18 1.37E-16 2.50 68.96 143 1708 membrane-enclosed lumen
GO:0043233 6.02E-18 1.56E-16 2.51 67.67 141 1676 organelle lumen
GO:0005681 1.45E-17 3.58E-16 8.29 5.32 33 132 spliceosomal complex
GO:0070013 1.56E-17 3.67E-16 2.50 66.25 138 1641 intracellular organelle lumen
GO:0043227 1.10E-14 2.35E-13 1.86 309.69 405 7670 membrane-bounded organelle
GO:0033279 1.78E-14 3.66E-13 7.68 4.76 28 118 ribosomal subunit
GO:0043231 3.30E-14 6.52E-13 1.84 309.44 403 7664 intracellular membrane-bounded organelle
GO:0005634 1.16E-11 2.12E-10 1.74 198.53 278 4917 nucleus
GO:0044451 6.02E-11 1.04E-09 3.12 18.61 51 461 nucleoplasm part
GO:0005623 6.10E-11 1.04E-09 3.70 589.86 630 14609 cell
GO:0005840 6.51E-11 1.07E-09 4.63 7.91 31 196 ribosome
GO:0044464 2.11E-10 3.16E-09 3.49 589.82 629 14608 cell part
GO:0043228 1.39E-09 1.91E-08 1.82 96.42 153 2388 non-membrane-bounded organelle
GO:0043232 1.39E-09 1.91E-08 1.82 96.42 153 2388 intracellular non-membrane-bounded organelle
GO:0031982 6.61E-09 8.83E-08 2.64 21.92 52 543 vesicle
GO:0031410 2.55E-08 3.32E-07 2.58 21.52 50 533 cytoplasmic vesicle
GO:0031988 1.87E-07 2.31E-06 2.66 17.03 41 422 membrane-bounded vesicle
GO:0016023 3.27E-07 3.93E-06 2.63 16.75 40 415 cytoplasmic membrane-bounded vesicle
GO:0012505 3.93E-07 4.62E-06 2.27 25.55 53 633 endomembrane system
GO:0005626 1.02E-05 9.67E-05 2.05 26.32 50 652 insoluble fraction
GO:0031967 2.41E-05 0.000220 2.08 22.81 44 565 organelle envelope
GO:0031975 2.62E-05 0.000235 2.07 22.89 44 567 envelope
GO:0000267 3.16E-05 0.000278 1.86 33.51 58 830 cell fraction
GO:0031090 5.39E-05 0.000422 1.78 37.26 62 923 organelle membrane
GO:0005624 9.54E-05 0.000682 1.91 25.67 46 636 membrane fraction
GO:0042995 0.000110 0.000780 2.06 19.21 37 476 cell projection
GO:0005768 0.000128 0.000893 2.44 11.06 25 274 endosome
GO:0005730 0.000431 0.002630 1.77 27.45 46 680 nucleolus
GO:0005694 0.000487 0.002901 2.02 16.31 31 404 chromosome
GO:0044427 0.001971 0.009189 1.98 13.32 25 330 chromosomal part
GO:0005740 0.006956 0.026435 1.76 15.46 26 383 mitochondrial envelope
GO:0015630 0.008251 0.031114 1.65 19.62 31 486 microtubule cytoskeleton
GO:0005794 0.017293 0.055116 1.43 32.54 45 806 Golgi apparatus
GO:0044429 0.042786 0.109515 1.42 22.40 31 555 mitochondrial part
GO:0044459 0.056957 0.141391 1.21 73.80 87 1828 plasma membrane part
GO:0005856 0.078246 0.171439 1.23 50.87 61 1260 cytoskeleton
GO:0044430 0.083034 0.177570 1.27 33.71 42 835 cytoskeletal part