PFAM ID:GO:0000165
Term :MAPKKK cascade
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
136ADORA2Badenosine A2b receptor
857CAV1caveolin 1_ caveolae protein_ 22kDa
859CAV3caveolin 3
875CBScystathionine-beta-synthase
1499CTNNB1catenin (cadherin-associated protein)_ beta 1_ 88kDa
1815DRD4dopamine receptor D4
1950EGFepidermal growth factor
2247FGF2fibroblast growth factor 2 (basic)
2357FPR1formyl peptide receptor 1
2904GRIN2Bglutamate receptor_ ionotropic_ N-methyl D-aspartate 2B
2914GRM4glutamate receptor_ metabotropic 4
3643INSRinsulin receptor
4214MAP3K1mitogen-activated protein kinase kinase kinase 1
4217MAP3K5mitogen-activated protein kinase kinase kinase 5
4293MAP3K9mitogen-activated protein kinase kinase kinase 9
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4296MAP3K11mitogen-activated protein kinase kinase kinase 11
4902NRTNneurturin
5027p2rx7purinergic receptor P2X_ ligand-gated ion channel_ 7
5058PAK1p21 protein (Cdc42/Rac)-activated kinase 1
5291PIK3CBphosphoinositide-3-kinase_ catalytic_ beta polypeptide
5578PRKCAprotein kinase C_ alpha
5594MAPK1mitogen-activated protein kinase 1
5599MAPK8mitogen-activated protein kinase 8
5601MAPK9mitogen-activated protein kinase 9
5602MAPK10mitogen-activated protein kinase 10
5606MAP2K3mitogen-activated protein kinase kinase 3
5608MAP2K6mitogen-activated protein kinase kinase 6
6416MAP2K4mitogen-activated protein kinase kinase 4
6647SOD1superoxide dismutase 1_ soluble
8767RIPK2receptor-interacting serine-threonine kinase 2
9459ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
9479MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1
51196PLCE1Phospholipase C_ epsilon 1