PFAM ID:GO:0003008
Term :system process
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
16AARSalanyl-tRNA synthetase
40ACCN1acid-sensing (proton-gated) ion channel 2
43ACHEacetylcholinesterase
88ACTN2actinin_ alpha 2
107ADCY1adenylate cyclase 1 (brain)
135ADORA2Aadenosine A2a receptor
136ADORA2Badenosine A2b receptor
156ADRBK1adrenergic_ beta_ receptor kinase 1
226ALDOAaldolase A_ fructose-bisphosphate
291SLC25A4Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator)_ member 4
348APOEapolipoprotein E
444ASPHaspartate beta-hydroxylase
525ATP6V1B1ATPase_ H+ transporting_ lysosomal 56/58kDa_ V1 subunit B1
596BCL2B-cell CLL/lymphoma 2
627BDNFbrain-derived neurotrophic factor
774CACNA1Bcalcium channel_ voltage-dependent_ N type_ alpha 1B subunit
836CASP3caspase 3_ apoptosis-related cysteine peptidase
857CAV1caveolin 1_ caveolae protein_ 22kDa
859CAV3caveolin 3
1020CDK5cyclin-dependent kinase 5
1103CHATcholine O-acetyltransferase
1128CHRM1cholinergic receptor_ muscarinic 1
1129CHRM2cholinergic receptor_ muscarinic 2
1131CHRM3cholinergic receptor_ muscarinic 3
1133CHRM5cholinergic receptor_ muscarinic 5
1241LTB4Rleukotriene B4 receptor
1312COMTcatechol-O-methyltransferase
1410CRYABcrystallin_ alpha B
1499CTNNB1catenin (cadherin-associated protein)_ beta 1_ 88kDa
1627DBN1drebrin 1
1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 1
1742DLG4discs_ large homolog 4 (Drosophila)
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1816DRD5dopamine receptor D5
1827RCAN1regulator of calcineurin 1
2339FNTAfarnesyltransferase_ CAAX box_ alpha
2566GABRG2gamma-aminobutyric acid (GABA) A receptor_ gamma 2
2572GAD2glutamate decarboxylase 2 (pancreatic islets and brain_ 65kDa)
2668GDNFglial cell derived neurotrophic factor
2740GLP1Rglucagon-like peptide 1 receptor
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein)_ beta polypeptide 1
2890GRIA1glutamate receptor_ ionotropic_ AMPA 1
2891GRIA2glutamate receptor_ ionotropic_ AMPA 2
2902GRIN1glutamate receptor_ ionotropic_ N-methyl D-aspartate 1
2903GRIN2Aglutamate receptor_ ionotropic_ N-methyl D-aspartate 2A
2904GRIN2Bglutamate receptor_ ionotropic_ N-methyl D-aspartate 2B
2906GRIN2Dglutamate receptor_ ionotropic_ N-methyl D-aspartate 2D
2911GRM1glutamate receptor_ metabotropic 1
2912GRM2glutamate receptor_ metabotropic 2
2913GRM3glutamate receptor_ metabotropic 3
2914GRM4glutamate receptor_ metabotropic 4
2915GRM5glutamate receptor_ metabotropic 5
2916GRM6glutamate receptor_ metabotropic 6
2917GRM7glutamate receptor_ metabotropic 7
2918GRM8glutamate receptor_ metabotropic 8
3060HCRThypocretin (orexin) neuropeptide precursor
3061HCRTR1hypocretin (orexin) receptor 1
3062HCRTR2hypocretin (orexin) receptor 2
3064HTThuntingtin
3162HMOX1heme oxygenase (decycling) 1
3351HTR1B5-hydroxytryptamine (serotonin) receptor 1B
3355HTR1F5-hydroxytryptamine (serotonin) receptor 1F
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C
3362HTR65-hydroxytryptamine (serotonin) receptor 6
3363HTR75-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
3479IGF1insulin-like growth factor 1 (somatomedin C)
3572IL6STinterleukin 6 signal transducer (gp130_ oncostatin M receptor)
3710ITPR3inositol 1_4_5-triphosphate receptor_ type 3
3736KCNA1potassium voltage-gated channel_ shaker-related subfamily_ member 1 (episodic ataxia with myokymia)
3767KCNJ11potassium inwardly-rectifying channel_ subfamily J_ member 11
4128MAOAmonoamine oxidase A
4628MYH10myosin_ heavy chain 10_ non-muscle
4803NGFnerve growth factor (beta polypeptide)
4842NOS1nitric oxide synthase 1 (neuronal)
4852NPYneuropeptide Y
4986OPRK1opioid receptor_ kappa 1
4987OPRL1opiate receptor-like 1
4988OPRM1opioid receptor_ mu 1
5023P2RX1purinergic receptor P2X_ ligand-gated ion channel_ 1
5024P2RX3purinergic receptor P2X_ ligand-gated ion channel_ 3
5025P2RX4purinergic receptor P2X_ ligand-gated ion channel_ 4
5027p2rx7purinergic receptor P2X_ ligand-gated ion channel_ 7
5467PPARDperoxisome proliferator-activated receptor delta
5468PPARGperoxisome proliferator-activated receptor gamma
5566PRKACAprotein kinase_ cAMP-dependent_ catalytic_ alpha
5577PRKAR2Bprotein kinase_ cAMP-dependent_ regulatory_ type II_ beta
5578PRKCAprotein kinase C_ alpha
5594MAPK1mitogen-activated protein kinase 1
5606MAP2K3mitogen-activated protein kinase kinase 3
5608MAP2K6mitogen-activated protein kinase kinase 6
5743PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
6011GRK1G protein-coupled receptor kinase 1
6096RORBRAR-related orphan receptor B
6286S100PS100 calcium binding protein P
6505SLC1A1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter_ system Xag)_ member 1
6506SLC1A2solute carrier family 1 (glial high affinity glutamate transporter)_ member 2
6507SLC1A3solute carrier family 1 (glial high affinity glutamate transporter)_ member 3
6529SLC6A1solute carrier family 6 (neurotransmitter transporter_ GABA)_ member 1
6530SLC6A2solute carrier family 6 (neurotransmitter transporter_ noradrenalin)_ member 2
6531SLC6A3solute carrier family 6 (neurotransmitter transporter_ dopamine)_ member 3
6532SLC6A4solute carrier family 6 (neurotransmitter transporter_ serotonin)_ member 4
6616SNAP25Synaptosomal-associated protein_ 25kDa
6647SOD1superoxide dismutase 1_ soluble
6804STX1Asyntaxin 1A (brain)
6812STXBP1syntaxin binding protein 1
6853SYN1synapsin I
6854SYN2synapsin II
6863TAC1tachykinin_ precursor 1
7054THtyrosine hydroxylase
7068THRBthyroid hormone receptor_ beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2_ avian)
7078TIMP3TIMP metallopeptidase inhibitor 3
7138TNNT1troponin T type 1 (skeletal_ slow)
7220TRPC1transient receptor potential cation channel_ subfamily C_ member 1
7314UBBubiquitin B
7345UCHL1Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
7419VDAC3voltage-dependent anion channel 3
7533YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein_ eta polypeptide
8224SYN3synapsin III
9001HAP1huntingtin-associated protein 1
9038TAAR5trace amine associated receptor 5
9152SLC6A5solute carrier family 6 (neurotransmitter transporter_ glycine)_ member 5
9948WDR1WD repeat domain 1
10594PRPF8PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
10815CPLX1complexin 1
10939AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
11188NISCHnischarin
27129HSPB7heat shock 27kDa protein family_ member 7 (cardiovascular)
29888STRN4striatin_ calmodulin binding protein 4
51196PLCE1Phospholipase C_ epsilon 1
116443GRIN3Aglutamate receptor_ ionotropic_ N-methyl-D-aspartate 3A
131890GRK7G protein-coupled receptor kinase 7