PFAM ID:GO:0007166
Term :cell surface receptor linked signal transduction
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
116ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
117ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
134ADORA1adenosine A1 receptor
135ADORA2Aadenosine A2a receptor
136ADORA2Badenosine A2b receptor
156ADRBK1adrenergic_ beta_ receptor kinase 1
207AKT1v-akt murine thymoma viral oncogene homolog 1
208AKT2V-akt murine thymoma viral oncogene homolog 2
334APLP2amyloid beta (A4) precursor-like protein 2
348APOEapolipoprotein E
573BAG1BCL2-associated athanogene
1012CDH13cadherin 13_ H-cadherin (heart)
1020CDK5cyclin-dependent kinase 5
1128CHRM1cholinergic receptor_ muscarinic 1
1129CHRM2cholinergic receptor_ muscarinic 2
1131CHRM3cholinergic receptor_ muscarinic 3
1132CHRM4cholinergic receptor_ muscarinic 4
1133CHRM5cholinergic receptor_ muscarinic 5
1241LTB4Rleukotriene B4 receptor
1268CNR1Cannabinoid receptor 1 (brain)
1269CNR2cannabinoid receptor 2 (macrophage)
1270CNTFciliary neurotrophic factor
1457CSNK2A1casein kinase 2_ alpha 1 polypeptide
1460CSNK2Bcasein kinase 2_ beta polypeptide
1499CTNNB1catenin (cadherin-associated protein)_ beta 1_ 88kDa
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1816DRD5dopamine receptor D5
1950EGFepidermal growth factor
2060EPS15epidermal growth factor receptor pathway substrate 15
2247FGF2fibroblast growth factor 2 (basic)
2339FNTAfarnesyltransferase_ CAAX box_ alpha
2357FPR1formyl peptide receptor 1
2550GABBR1gamma-aminobutyric acid (GABA) B receptor_ 1
2554GABRA1gamma-aminobutyric acid (GABA) A receptor_ alpha 1
2566GABRG2gamma-aminobutyric acid (GABA) A receptor_ gamma 2
2674GFRA1GDNF family receptor alpha 1
2675GFRA2GDNF family receptor alpha 2
2740GLP1Rglucagon-like peptide 1 receptor
2770GNAI1guanine nucleotide binding protein (G protein)_ alpha inhibiting activity polypeptide 1
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein)_ beta polypeptide 1
2798GNRHRgonadotropin-releasing hormone receptor
2826CCR10chemokine (C-C motif) receptor 10
2847MCHR1melanin-concentrating hormone receptor 1
2868GRK4G protein-coupled receptor kinase 4
2869GRK5G protein-coupled receptor kinase 5
2870GRK6G protein-coupled receptor kinase 6
2892GRIA3glutamate receptor_ ionotrophic_ AMPA 3
2893GRIA4glutamate receptor_ ionotrophic_ AMPA 4
2902GRIN1glutamate receptor_ ionotropic_ N-methyl D-aspartate 1
2903GRIN2Aglutamate receptor_ ionotropic_ N-methyl D-aspartate 2A
2904GRIN2Bglutamate receptor_ ionotropic_ N-methyl D-aspartate 2B
2905GRIN2Cglutamate receptor_ ionotropic_ N-methyl D-aspartate 2C
2911GRM1glutamate receptor_ metabotropic 1
2912GRM2glutamate receptor_ metabotropic 2
2913GRM3glutamate receptor_ metabotropic 3
2914GRM4glutamate receptor_ metabotropic 4
2915GRM5glutamate receptor_ metabotropic 5
2916GRM6glutamate receptor_ metabotropic 6
2917GRM7glutamate receptor_ metabotropic 7
2918GRM8glutamate receptor_ metabotropic 8
2931GSK3Aglycogen synthase kinase 3 alpha
2932GSK3Bglycogen synthase kinase 3 beta
3060HCRThypocretin (orexin) neuropeptide precursor
3061HCRTR1hypocretin (orexin) receptor 1
3062HCRTR2hypocretin (orexin) receptor 2
3064HTThuntingtin
3084NRG1neuregulin 1
3091HIF1Ahypoxia inducible factor 1_ alpha subunit (basic helix-loop-helix transcription factor)
3350HTR1A5-hydroxytryptamine (serotonin) receptor 1A
3351HTR1B5-hydroxytryptamine (serotonin) receptor 1B
3355HTR1F5-hydroxytryptamine (serotonin) receptor 1F
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C
3362HTR65-hydroxytryptamine (serotonin) receptor 6
3363HTR75-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
3479IGF1insulin-like growth factor 1 (somatomedin C)
3570IL6Rinterleukin 6 receptor
3572IL6STinterleukin 6 signal transducer (gp130_ oncostatin M receptor)
3643INSRinsulin receptor
3654IRAK1interleukin-1 receptor-associated kinase 1
3674ITGA2Bintegrin_ alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex_ antigen CD41)
3710ITPR3inositol 1_4_5-triphosphate receptor_ type 3
3716JAK1Janus kinase 1
3717JAK2Janus kinase 2
3718JAK3Janus kinase 3
3725JUNjun proto-oncogene
3791KDRkinase insert domain receptor (a type III receptor tyrosine kinase)
3977LIFRleukemia inhibitory factor receptor alpha
4214MAP3K1mitogen-activated protein kinase kinase kinase 1
4803NGFnerve growth factor (beta polypeptide)
4852NPYneuropeptide Y
4902NRTNneurturin
4914NTRK1neurotrophic tyrosine kinase_ receptor_ type 1
4916NTRK3neurotrophic tyrosine kinase_ receptor_ type 3
4985OPRD1opioid receptor_ delta 1
4986OPRK1opioid receptor_ kappa 1
4987OPRL1opiate receptor-like 1
4988OPRM1opioid receptor_ mu 1
5027p2rx7purinergic receptor P2X_ ligand-gated ion channel_ 7
5028P2RY1purinergic receptor P2Y_ G-protein coupled_ 1
5029P2RY2purinergic receptor P2Y_ G-protein coupled_ 2
5030P2RY4pyrimidinergic receptor P2Y_ G-protein coupled_ 4
5031P2RY6pyrimidinergic receptor P2Y_ G-protein coupled_ 6
5032P2RY11purinergic receptor P2Y_ G-protein coupled_ 11
5291PIK3CBphosphoinositide-3-kinase_ catalytic_ beta polypeptide
5295PIK3R1phosphoinositide-3-kinase_ regulatory subunit 1 (alpha)
5300PIN1peptidylprolyl cis/trans isomerase_ NIMA-interacting 1
5567PRKACBprotein kinase_ cAMP-dependent_ catalytic_ beta
5578PRKCAprotein kinase C_ alpha
5580PRKCDprotein kinase C_ delta
5590PRKCZProtein kinase C_ zeta
5594MAPK1mitogen-activated protein kinase 1
5663PSEN1presenilin 1
5664PSEN2presenilin 2 (Alzheimer disease 4)
5727PTCH1patched 1
5728PTENphosphatase and tensin homolog
6011GRK1G protein-coupled receptor kinase 1
6714SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
6776STAT5Asignal transducer and activator of transcription 5A
6777STAT5Bsignal transducer and activator of transcription 5B
6863TAC1tachykinin_ precursor 1
6866TAC3tachykinin 3
7052TGM2transglutaminase 2 (C polypeptide_ protein-glutamine-gamma-glutamyltransferase)
7204TRIOtriple functional domain (PTPRF interacting)
7249TSC2tuberous sclerosis 2
7323UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog_ yeast)
7334UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog_ yeast)
7422VEGFAvascular endothelial growth factor A
7855FZD5frizzled homolog 5 (Drosophila)
8239USP9Xubiquitin specific peptidase 9_ X-linked
8408ULK1unc-51-like kinase 1 (C. elegans)
8517IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells_ kinase gamma
8660IRS2insulin receptor substrate 2
8851CDK5R1cyclin-dependent kinase 5_ regulatory subunit 1 (p35)
8945BTRCbeta-transducin repeat containing
9038TAAR5trace amine associated receptor 5
9241NOGnoggin
9252RPS6KA5ribosomal protein S6 kinase_ 90kDa_ polypeptide 5
9287TAAR2trace amine associated receptor 2
9288TAAR3trace amine associated receptor 3 (gene/pseudogene)
9934P2RY14purinergic receptor P2Y_ G-protein coupled_ 14
10273STUB1STIP1 homology and U-box containing protein 1_ E3 ubiquitin protein ligase
23636NUP62nucleoporin 62kDa
50506DUOX2dual oxidase 2
51176LEF1lymphoid enhancer-binding factor 1
51196PLCE1Phospholipase C_ epsilon 1
51701NLKnemo-like kinase
53829P2RY13purinergic receptor P2Y_ G-protein coupled_ 13
56033BARX1BARX homeobox 1
56848SPHK2sphingosine kinase 2
59343SENP2SUMO1/sentrin/SMT3 specific peptidase 2
64805P2RY12purinergic receptor P2Y_ G-protein coupled_ 12
83551TAAR8trace amine associated receptor 8
84539MCHR2melanin-concentrating hormone receptor 2
116444GRIN3Bglutamate receptor_ ionotropic_ N-methyl-D-aspartate 3B
134860TAAR9trace amine associated receptor 9 (gene/pseudogene)
134864TAAR1trace amine associated receptor 1
286530P2RY8purinergic receptor P2Y_ G-protein coupled_ 8
319100TAAR6trace amine associated receptor 6