PFAM ID:GO:0007243
Term :protein kinase cascade
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
136ADORA2Badenosine A2b receptor
207AKT1v-akt murine thymoma viral oncogene homolog 1
387RHOAras homolog gene family_ member A
834CASP1caspase 1_ apoptosis-related cysteine peptidase (interleukin 1_ beta_ convertase)
841CASP8caspase 8_ apoptosis-related cysteine peptidase
847CATcatalase
857CAV1caveolin 1_ caveolae protein_ 22kDa
859CAV3caveolin 3
875CBScystathionine-beta-synthase
1020CDK5cyclin-dependent kinase 5
1147CHUKconserved helix-loop-helix ubiquitous kinase
1270CNTFciliary neurotrophic factor
1499CTNNB1catenin (cadherin-associated protein)_ beta 1_ 88kDa
1612DAPK1death-associated protein kinase 1
1613DAPK3death-associated protein kinase 3
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1950EGFepidermal growth factor
2247FGF2fibroblast growth factor 2 (basic)
2357FPR1formyl peptide receptor 1
2904GRIN2Bglutamate receptor_ ionotropic_ N-methyl D-aspartate 2B
2914GRM4glutamate receptor_ metabotropic 4
3162HMOX1heme oxygenase (decycling) 1
3479IGF1insulin-like growth factor 1 (somatomedin C)
3570IL6Rinterleukin 6 receptor
3572IL6STinterleukin 6 signal transducer (gp130_ oncostatin M receptor)
3643INSRinsulin receptor
3654IRAK1interleukin-1 receptor-associated kinase 1
3716JAK1Janus kinase 1
3717JAK2Janus kinase 2
3718JAK3Janus kinase 3
4214MAP3K1mitogen-activated protein kinase kinase kinase 1
4217MAP3K5mitogen-activated protein kinase kinase kinase 5
4293MAP3K9mitogen-activated protein kinase kinase kinase 9
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4296MAP3K11mitogen-activated protein kinase kinase kinase 11
4902NRTNneurturin
5027p2rx7purinergic receptor P2X_ ligand-gated ion channel_ 7
5058PAK1p21 protein (Cdc42/Rac)-activated kinase 1
5290PIK3CAphosphoinositide-3-kinase_ catalytic_ alpha polypeptide
5291PIK3CBphosphoinositide-3-kinase_ catalytic_ beta polypeptide
5295PIK3R1phosphoinositide-3-kinase_ regulatory subunit 1 (alpha)
5467PPARDperoxisome proliferator-activated receptor delta
5566PRKACAprotein kinase_ cAMP-dependent_ catalytic_ alpha
5567PRKACBprotein kinase_ cAMP-dependent_ catalytic_ beta
5568PRKACGprotein kinase_ cAMP-dependent_ catalytic_ gamma
5578PRKCAprotein kinase C_ alpha
5594MAPK1mitogen-activated protein kinase 1
5599MAPK8mitogen-activated protein kinase 8
5601MAPK9mitogen-activated protein kinase 9
5602MAPK10mitogen-activated protein kinase 10
5606MAP2K3mitogen-activated protein kinase kinase 3
5608MAP2K6mitogen-activated protein kinase kinase 6
5728PTENphosphatase and tensin homolog
6199RPS6KB2ribosomal protein S6 kinase_ 70kDa_ polypeptide 2
6416MAP2K4mitogen-activated protein kinase kinase 4
6647SOD1superoxide dismutase 1_ soluble
6714SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
6776STAT5Asignal transducer and activator of transcription 5A
6777STAT5Bsignal transducer and activator of transcription 5B
7052TGM2transglutaminase 2 (C polypeptide_ protein-glutamine-gamma-glutamyltransferase)
7099TLR4toll-like receptor 4
7188TRAF5TNF receptor-associated factor 5
7249TSC2tuberous sclerosis 2
7334UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog_ yeast)
8517IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells_ kinase gamma
8767RIPK2receptor-interacting serine-threonine kinase 2
8797TNFRSF10Atumor necrosis factor receptor superfamily_ member 10a
8878SQSTM1sequestosome 1
9252RPS6KA5ribosomal protein S6 kinase_ 90kDa_ polypeptide 5
9459ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
9479MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1
9908G3BP2GTPase activating protein (SH3 domain) binding protein 2
10342TFGTRK-fused gene
22858ICKintestinal cell (MAK-like) kinase
23390ZDHHC17zinc finger_ DHHC-type containing 17
23604DAPK2death-associated protein kinase 2
23636NUP62nucleoporin 62kDa
51196PLCE1Phospholipase C_ epsilon 1
51701NLKnemo-like kinase
54503ZDHHC13zinc finger_ DHHC-type containing 13