PFAM ID:GO:0019932
Term :second-messenger-mediated signaling
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
135ADORA2Aadenosine A2a receptor
136ADORA2Badenosine A2b receptor
348APOEapolipoprotein E
701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)
1012CDH13cadherin 13_ H-cadherin (heart)
1128CHRM1cholinergic receptor_ muscarinic 1
1129CHRM2cholinergic receptor_ muscarinic 2
1133CHRM5cholinergic receptor_ muscarinic 5
1241LTB4Rleukotriene B4 receptor
1268CNR1Cannabinoid receptor 1 (brain)
1269CNR2cannabinoid receptor 2 (macrophage)
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1816DRD5dopamine receptor D5
1827RCAN1regulator of calcineurin 1
2237FEN1flap structure-specific endonuclease 1
2357FPR1formyl peptide receptor 1
2740GLP1Rglucagon-like peptide 1 receptor
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein)_ beta polypeptide 1
2847MCHR1melanin-concentrating hormone receptor 1
2869GRK5G protein-coupled receptor kinase 5
2914GRM4glutamate receptor_ metabotropic 4
2915GRM5glutamate receptor_ metabotropic 5
3062HCRTR2hypocretin (orexin) receptor 2
3148HMGB2high-mobility group box 2
3351HTR1B5-hydroxytryptamine (serotonin) receptor 1B
3355HTR1F5-hydroxytryptamine (serotonin) receptor 1F
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C
3362HTR65-hydroxytryptamine (serotonin) receptor 6
3363HTR75-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
3479IGF1insulin-like growth factor 1 (somatomedin C)
4852NPYneuropeptide Y
4985OPRD1opioid receptor_ delta 1
4986OPRK1opioid receptor_ kappa 1
4987OPRL1opiate receptor-like 1
4988OPRM1opioid receptor_ mu 1
5024P2RX3purinergic receptor P2X_ ligand-gated ion channel_ 3
5025P2RX4purinergic receptor P2X_ ligand-gated ion channel_ 4
5026P2RX5purinergic receptor P2X_ ligand-gated ion channel_ 5
5028P2RY1purinergic receptor P2Y_ G-protein coupled_ 1
5029P2RY2purinergic receptor P2Y_ G-protein coupled_ 2
5030P2RY4pyrimidinergic receptor P2Y_ G-protein coupled_ 4
5031P2RY6pyrimidinergic receptor P2Y_ G-protein coupled_ 6
5032P2RY11purinergic receptor P2Y_ G-protein coupled_ 11
5286PIK3C2Aphosphoinositide-3-kinase_ class 2_ alpha polypeptide
5289PIK3C3phosphoinositide-3-kinase_ class 3
5290PIK3CAphosphoinositide-3-kinase_ catalytic_ alpha polypeptide
5291PIK3CBphosphoinositide-3-kinase_ catalytic_ beta polypeptide
5567PRKACBprotein kinase_ cAMP-dependent_ catalytic_ beta
7052TGM2transglutaminase 2 (C polypeptide_ protein-glutamine-gamma-glutamyltransferase)
22953P2RX2purinergic receptor P2X_ ligand-gated ion channel_ 2
51196PLCE1Phospholipase C_ epsilon 1
64805P2RY12purinergic receptor P2Y_ G-protein coupled_ 12