PFAM ID:GO:0030163
Term :protein catabolic process
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
Note that a login is required for the HD Research CrossRoads database.
Entrez Gene IDApproved SymbolApproved Name
207AKT1v-akt murine thymoma viral oncogene homolog 1
331XIAPX-linked inhibitor of apoptosis
348APOEapolipoprotein E
701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)
726CAPN5calpain 5
823CAPN1calpain 1_ (mu/I) large subunit
824CAPN2calpain 2_ (m/II) large subunit
834CASP1caspase 1_ apoptosis-related cysteine peptidase (interleukin 1_ beta_ convertase)
835CASP2caspase 2_ apoptosis-related cysteine peptidase
836CASP3caspase 3_ apoptosis-related cysteine peptidase
839CASP6caspase 6_ apoptosis-related cysteine peptidase
840CASP7caspase 7_ apoptosis-related cysteine peptidase
841CASP8caspase 8_ apoptosis-related cysteine peptidase
842CASP9caspase 9_ apoptosis-related cysteine peptidase
891CCNB1cyclin B1
1508CTSBcathepsin B
1509CTSDcathepsin D
1514CTSL1cathepsin L1
1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 1
2475MTORmechanistic target of rapamycin (serine/threonine kinase)
2903GRIN2Aglutamate receptor_ ionotropic_ N-methyl D-aspartate 2A
3066HDAC2histone deacetylase 2
3093UBE2Kubiquitin-conjugating enzyme E2K (UBC1 homolog_ yeast)
3818KLKB1kallikrein B_ plasma (Fletcher factor) 1
4319MMP10matrix metallopeptidase 10 (stromelysin 2)
4323MMP14matrix metallopeptidase 14 (membrane-inserted)
4905NSFN-ethylmaleimide-sensitive factor
5071PARK2parkinson protein 2_ E3 ubiquitin protein ligase (parkin)
5655KLK10kallikrein-related peptidase 10
5663PSEN1presenilin 1
5664PSEN2presenilin 2 (Alzheimer disease 4)
5682PSMA1proteasome (prosome_ macropain) subunit_ alpha type_ 1
5686PSMA5proteasome (prosome_ macropain) subunit_ alpha type_ 5
5688PSMA7proteasome (prosome_ macropain) subunit_ alpha type_ 7
5690PSMB2proteasome (prosome_ macropain) subunit_ beta type_ 2
5691PSMB3proteasome (prosome_ macropain) subunit_ beta type_ 3
5693PSMB5proteasome (prosome_ macropain) subunit_ beta type_ 5
5694PSMB6proteasome (prosome_ macropain) subunit_ beta type_ 6
5695PSMB7proteasome (prosome_ macropain) subunit_ beta type_ 7
5701PSMC2proteasome (prosome_ macropain) 26S subunit_ ATPase_ 2
5702PSMC3proteasome (prosome_ macropain) 26S subunit_ ATPase_ 3
5705PSMC5proteasome (prosome_ macropain) 26S subunit_ ATPase_ 5
5706PSMC6proteasome (prosome_ macropain) 26S subunit_ ATPase_ 6
5708PSMD2proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 2
5709PSMD3proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 3
5710PSMD4proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 4
5713PSMD7proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 7
5714PSMD8proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 8
5717PSMD11proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 11
5903RANBP2RAN binding protein 2
6477SIAH1seven in absentia homolog 1 (Drosophila)
6500SKP1S-phase kinase-associated protein 1
6612SUMO3SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
7078TIMP3TIMP metallopeptidase inhibitor 3
7251TSG101tumor susceptibility gene 101
7314UBBubiquitin B
7317UBA1ubiquitin-like modifier activating enzyme 1
7319UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)
7322UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog_ yeast)
7323UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog_ yeast)
7328UBE2Hubiquitin-conjugating enzyme E2H (UBC8 homolog_ yeast)
7329UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog_ yeast)
7334UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog_ yeast)
7336UBE2V2ubiquitin-conjugating enzyme E2 variant 2
7337UBE3Aubiquitin protein ligase E3A
7341SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
7345UCHL1Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
7347UCHL3ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
7353UFD1Lubiquitin fusion degradation 1 like (yeast)
7415VCPvalosin-containing protein
8239USP9Xubiquitin specific peptidase 9_ X-linked
8453CUL2cullin 2
8454CUL1cullin 1
8510MMP23Bmatrix metallopeptidase 23B
8878SQSTM1sequestosome 1
8945BTRCbeta-transducin repeat containing
9184BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)
9730VPRBPVpr (HIV-1) binding protein
9924PAN2PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
10054UBA2ubiquitin-like modifier activating enzyme 2
10055SAE1SUMO1 activating enzyme subunit 1
10197PSME3proteasome (prosome_ macropain) activator subunit 3 (PA28 gamma; Ki)
10213PSMD14proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 14
10273STUB1STIP1 homology and U-box containing protein 1_ E3 ubiquitin protein ligase
10533ATG7ATG7 autophagy related 7 homolog (S. cerevisiae)
10939AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
11012KLK11kallikrein-related peptidase 11
23077MYCBP2MYC binding protein 2
25825BACE2beta-site APP-cleaving enzyme 2
26260FBXO25F-box protein 25
27429HTRA2HtrA serine peptidase 2
28972SPCS1signal peptidase complex subunit 1 homolog (S. cerevisiae)
51343FZR1fizzy/cell division cycle 20 related 1 (Drosophila)
55666NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)
59343SENP2SUMO1/sentrin/SMT3 specific peptidase 2
64699TMPRSS3transmembrane protease_ serine 3
84447SYVN1synovial apoptosis inhibitor 1_ synoviolin
112398EGLN2egl nine homolog 2 (C. elegans)
114769CARD16caspase recruitment domain family_ member 16
115426UHRF2ubiquitin-like with PHD and ring finger domains 2_ E3 ubiquitin protein ligase
120329CASP12caspase 12 (gene/pseudogene)