PFAM ID:GO:0042221
Term :response to chemical stimulus
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
16AARSalanyl-tRNA synthetase
107ADCY1adenylate cyclase 1 (brain)
207AKT1v-akt murine thymoma viral oncogene homolog 1
208AKT2V-akt murine thymoma viral oncogene homolog 2
249ALPLalkaline phosphatase_ liver/bone/kidney
348APOEapolipoprotein E
513ATP5DATP synthase_ H+ transporting_ mitochondrial F1 complex_ delta subunit
538ATP7AATPase_ Cu++ transporting_ alpha polypeptide
581BAXBCL2-associated X protein
596BCL2B-cell CLL/lymphoma 2
627BDNFbrain-derived neurotrophic factor
836CASP3caspase 3_ apoptosis-related cysteine peptidase
841CASP8caspase 8_ apoptosis-related cysteine peptidase
847CATcatalase
857CAV1caveolin 1_ caveolae protein_ 22kDa
1012CDH13cadherin 13_ H-cadherin (heart)
1020CDK5cyclin-dependent kinase 5
1072CFL1cofilin 1 (non-muscle)
1385CREB1cAMP responsive element binding protein 1
1387CREBBPCREB binding protein
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1827RCAN1regulator of calcineurin 1
2071ERCC3excision repair cross-complementing rodent repair deficiency_ complementation group 3 (xeroderma pigmentosum group B complementing)
2243FGAfibrinogen alpha chain
2247FGF2fibroblast growth factor 2 (basic)
2357FPR1formyl peptide receptor 1
2475MTORmechanistic target of rapamycin (serine/threonine kinase)
2752GLULglutamate-ammonia ligase
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein)_ beta polypeptide 1
2805GOT1glutamic-oxaloacetic transaminase 1_ soluble (aspartate aminotransferase 1)
2826CCR10chemokine (C-C motif) receptor 10
2891GRIA2glutamate receptor_ ionotropic_ AMPA 2
2902GRIN1glutamate receptor_ ionotropic_ N-methyl D-aspartate 1
2903GRIN2Aglutamate receptor_ ionotropic_ N-methyl D-aspartate 2A
2904GRIN2Bglutamate receptor_ ionotropic_ N-methyl D-aspartate 2B
2931GSK3Aglycogen synthase kinase 3 alpha
3064HTThuntingtin
3091HIF1Ahypoxia inducible factor 1_ alpha subunit (basic helix-loop-helix transcription factor)
3148HMGB2high-mobility group box 2
3162HMOX1heme oxygenase (decycling) 1
3300DNAJB2DnaJ (Hsp40) homolog_ subfamily B_ member 2
3301DNAJA1DnaJ (Hsp40) homolog_ subfamily A_ member 1
3306HSPA2heat shock 70kDa protein 2
3308HSPA4heat shock 70kDa protein 4
3312HSPA8heat shock 70kDa protein 8
3315HSPB1heat shock 27kDa protein 1
3320HSP90AA1heat shock protein 90kDa alpha (cytosolic)_ class A member 1
3337DNAJB1DnaJ (Hsp40) homolog_ subfamily B_ member 1
3351HTR1B5-hydroxytryptamine (serotonin) receptor 1B
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C
3570IL6Rinterleukin 6 receptor
3572IL6STinterleukin 6 signal transducer (gp130_ oncostatin M receptor)
3643INSRinsulin receptor
3654IRAK1interleukin-1 receptor-associated kinase 1
3708ITPR1inositol 1_4_5-triphosphate receptor_ type 1
3709ITPR2inositol 1_4_5-triphosphate receptor_ type 2
3710ITPR3inositol 1_4_5-triphosphate receptor_ type 3
3716JAK1Janus kinase 1
3717JAK2Janus kinase 2
3725JUNjun proto-oncogene
3767KCNJ11potassium inwardly-rectifying channel_ subfamily J_ member 11
3791KDRkinase insert domain receptor (a type III receptor tyrosine kinase)
3977LIFRleukemia inhibitory factor receptor alpha
4323MMP14matrix metallopeptidase 14 (membrane-inserted)
4521NUDT1nudix (nucleoside diphosphate linked moiety X)-type motif 1
4842NOS1nitric oxide synthase 1 (neuronal)
4852NPYneuropeptide Y
4891SLC11A2solute carrier family 11 (proton-coupled divalent metal ion transporters)_ member 2
5023P2RX1purinergic receptor P2X_ ligand-gated ion channel_ 1
5024P2RX3purinergic receptor P2X_ ligand-gated ion channel_ 3
5025P2RX4purinergic receptor P2X_ ligand-gated ion channel_ 4
5027p2rx7purinergic receptor P2X_ ligand-gated ion channel_ 7
5291PIK3CBphosphoinositide-3-kinase_ catalytic_ beta polypeptide
5295PIK3R1phosphoinositide-3-kinase_ regulatory subunit 1 (alpha)
5468PPARGperoxisome proliferator-activated receptor gamma
5566PRKACAprotein kinase_ cAMP-dependent_ catalytic_ alpha
5567PRKACBprotein kinase_ cAMP-dependent_ catalytic_ beta
5568PRKACGprotein kinase_ cAMP-dependent_ catalytic_ gamma
5573PRKAR1Aprotein kinase_ cAMP-dependent_ regulatory_ type I_ alpha (tissue specific extinguisher 1)
5575PRKAR1Bprotein kinase_ cAMP-dependent_ regulatory_ type I_ beta
5576PRKAR2Aprotein kinase_ cAMP-dependent_ regulatory_ type II_ alpha
5577PRKAR2Bprotein kinase_ cAMP-dependent_ regulatory_ type II_ beta
5578PRKCAprotein kinase C_ alpha
5580PRKCDprotein kinase C_ delta
5590PRKCZProtein kinase C_ zeta
5594MAPK1mitogen-activated protein kinase 1
5604MAP2K1mitogen-activated protein kinase kinase 1
5621PRNPprion protein
5743PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
6256RXRAretinoid X receptor_ alpha
6352CCL5chemokine (C-C motif) ligand 5
6506SLC1A2solute carrier family 1 (glial high affinity glutamate transporter)_ member 2
6507SLC1A3solute carrier family 1 (glial high affinity glutamate transporter)_ member 3
6531SLC6A3solute carrier family 6 (neurotransmitter transporter_ dopamine)_ member 3
6570SLC18A1solute carrier family 18 (vesicular monoamine)_ member 1
6571SLC18A2solute carrier family 18 (vesicular monoamine)_ member 2
6647SOD1superoxide dismutase 1_ soluble
6714SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
6776STAT5Asignal transducer and activator of transcription 5A
6777STAT5Bsignal transducer and activator of transcription 5B
6786STIM1stromal interaction molecule 1
6829SUPT5Hsuppressor of Ty 5 homolog (S. cerevisiae)
7054THtyrosine hydroxylase
7067THRAthyroid hormone receptor_ alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog_ avian)
7078TIMP3TIMP metallopeptidase inhibitor 3
7099TLR4toll-like receptor 4
7157TP53tumor protein p53
7220TRPC1transient receptor potential cation channel_ subfamily C_ member 1
7248TSC1tuberous sclerosis 1
7249TSC2tuberous sclerosis 2
7351UCP2uncoupling protein 2 (mitochondrial_ proton carrier)
7415VCPvalosin-containing protein
7422VEGFAvascular endothelial growth factor A
8288EPXeosinophil peroxidase
8660IRS2insulin receptor substrate 2
8942KYNUkynureninase (L-kynurenine hydrolase)
8988HSPB3heat shock 27kDa protein 3
9049AIParyl hydrocarbon receptor interacting protein
9252RPS6KA5ribosomal protein S6 kinase_ 90kDa_ polypeptide 5
9429ABCG2ATP-binding cassette_ sub-family G (WHITE)_ member 2
9525VPS4Bvacuolar protein sorting 4 homolog B (S. cerevisiae)
9993DGCR2DiGeorge syndrome critical region gene 2
10049DNAJB6DnaJ (Hsp40) homolog_ subfamily B_ member 6
10202DHRS2dehydrogenase/reductase (SDR family) member 2
11080DNAJB4DnaJ (Hsp40) homolog_ subfamily B_ member 4
22933SIRT2sirtuin 2
23636NUP62nucleoporin 62kDa
25788RAD54BRAD54 homolog B (S. cerevisiae)
27129HSPB7heat shock 27kDa protein family_ member 7 (cardiovascular)
27161EIF2C2Eukaryotic translation initiation factor 2C_ 2
50506DUOX2dual oxidase 2
51593SRRTserrate RNA effector molecule homolog (Arabidopsis)
54583EGLN1egl nine homolog 1 (C. elegans)
64714PDIA2protein disulfide isomerase family A_ member 2
112398EGLN2egl nine homolog 2 (C. elegans)
116085SLC22A12solute carrier family 22 (organic anion/urate transporter)_ member 12
116443GRIN3Aglutamate receptor_ ionotropic_ N-methyl-D-aspartate 3A
120329CASP12caspase 12 (gene/pseudogene)