PFAM ID:GO:0044093
Term :positive regulation of molecular function
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
116ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
117ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
118ADD1adducin 1 (alpha)
135ADORA2Aadenosine A2a receptor
136ADORA2Badenosine A2b receptor
207AKT1v-akt murine thymoma viral oncogene homolog 1
317APAF1apoptotic peptidase activating factor 1
348APOEapolipoprotein E
538ATP7AATPase_ Cu++ transporting_ alpha polypeptide
581BAXBCL2-associated X protein
596BCL2B-cell CLL/lymphoma 2
842CASP9caspase 9_ apoptosis-related cysteine peptidase
847CATcatalase
857CAV1caveolin 1_ caveolae protein_ 22kDa
891CCNB1cyclin B1
1020CDK5cyclin-dependent kinase 5
1128CHRM1cholinergic receptor_ muscarinic 1
1129CHRM2cholinergic receptor_ muscarinic 2
1241LTB4Rleukotriene B4 receptor
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1816DRD5dopamine receptor D5
1950EGFepidermal growth factor
2247FGF2fibroblast growth factor 2 (basic)
2357FPR1formyl peptide receptor 1
2668GDNFglial cell derived neurotrophic factor
2740GLP1Rglucagon-like peptide 1 receptor
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein)_ beta polypeptide 1
2914GRM4glutamate receptor_ metabotropic 4
2915GRM5glutamate receptor_ metabotropic 5
2956MSH6mutS homolog 6 (E. coli)
3062HCRTR2hypocretin (orexin) receptor 2
3091HIF1Ahypoxia inducible factor 1_ alpha subunit (basic helix-loop-helix transcription factor)
3092HIP1huntingtin interacting protein 1
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C
3551IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells_ kinase beta
3643INSRinsulin receptor
3654IRAK1interleukin-1 receptor-associated kinase 1
4214MAP3K1mitogen-activated protein kinase kinase kinase 1
4217MAP3K5mitogen-activated protein kinase kinase kinase 5
4293MAP3K9mitogen-activated protein kinase kinase kinase 9
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4296MAP3K11mitogen-activated protein kinase kinase kinase 11
4436MSH2mutS homolog 2_ colon cancer_ nonpolyposis type 1 (E. coli)
4437MSH3mutS homolog 3 (E. coli)
4914NTRK1neurotrophic tyrosine kinase_ receptor_ type 1
5023P2RX1purinergic receptor P2X_ ligand-gated ion channel_ 1
5028P2RY1purinergic receptor P2Y_ G-protein coupled_ 1
5029P2RY2purinergic receptor P2Y_ G-protein coupled_ 2
5030P2RY4pyrimidinergic receptor P2Y_ G-protein coupled_ 4
5031P2RY6pyrimidinergic receptor P2Y_ G-protein coupled_ 6
5032P2RY11purinergic receptor P2Y_ G-protein coupled_ 11
5058PAK1p21 protein (Cdc42/Rac)-activated kinase 1
5291PIK3CBphosphoinositide-3-kinase_ catalytic_ beta polypeptide
5300PIN1peptidylprolyl cis/trans isomerase_ NIMA-interacting 1
5347PLK1polo-like kinase 1
5604MAP2K1mitogen-activated protein kinase kinase 1
5606MAP2K3mitogen-activated protein kinase kinase 3
5608MAP2K6mitogen-activated protein kinase kinase 6
5663PSEN1presenilin 1
5664PSEN2presenilin 2 (Alzheimer disease 4)
5682PSMA1proteasome (prosome_ macropain) subunit_ alpha type_ 1
5686PSMA5proteasome (prosome_ macropain) subunit_ alpha type_ 5
5688PSMA7proteasome (prosome_ macropain) subunit_ alpha type_ 7
5690PSMB2proteasome (prosome_ macropain) subunit_ beta type_ 2
5691PSMB3proteasome (prosome_ macropain) subunit_ beta type_ 3
5693PSMB5proteasome (prosome_ macropain) subunit_ beta type_ 5
5694PSMB6proteasome (prosome_ macropain) subunit_ beta type_ 6
5695PSMB7proteasome (prosome_ macropain) subunit_ beta type_ 7
5701PSMC2proteasome (prosome_ macropain) 26S subunit_ ATPase_ 2
5702PSMC3proteasome (prosome_ macropain) 26S subunit_ ATPase_ 3
5705PSMC5proteasome (prosome_ macropain) 26S subunit_ ATPase_ 5
5706PSMC6proteasome (prosome_ macropain) 26S subunit_ ATPase_ 6
5708PSMD2proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 2
5709PSMD3proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 3
5710PSMD4proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 4
5713PSMD7proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 7
5714PSMD8proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 8
5717PSMD11proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 11
6188RPS3ribosomal protein S3
6500SKP1S-phase kinase-associated protein 1
6597SMARCA4SWI/SNF related_ matrix associated_ actin dependent regulator of chromatin_ subfamily a_ member 4
6647SOD1superoxide dismutase 1_ soluble
6786STIM1stromal interaction molecule 1
7052TGM2transglutaminase 2 (C polypeptide_ protein-glutamine-gamma-glutamyltransferase)
7157TP53tumor protein p53
7248TSC1tuberous sclerosis 1
7249TSC2tuberous sclerosis 2
7314UBBubiquitin B
7334UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog_ yeast)
7376NR1H2nuclear receptor subfamily 1_ group H_ member 2
7415VCPvalosin-containing protein
8454CUL1cullin 1
8721EDF1endothelial differentiation-related factor 1
8767RIPK2receptor-interacting serine-threonine kinase 2
8797TNFRSF10Atumor necrosis factor receptor superfamily_ member 10a
8945BTRCbeta-transducin repeat containing
10062NR1H3nuclear receptor subfamily 1_ group H_ member 3
10197PSME3proteasome (prosome_ macropain) activator subunit 3 (PA28 gamma; Ki)
10213PSMD14proteasome (prosome_ macropain) 26S subunit_ non-ATPase_ 14
10487CAP1CAP_ adenylate cyclase-associated protein 1 (yeast)
51196PLCE1Phospholipase C_ epsilon 1
51343FZR1fizzy/cell division cycle 20 related 1 (Drosophila)
55081IFT57intraflagellar transport 57 homolog (Chlamydomonas)
56848SPHK2sphingosine kinase 2