PFAM ID:GO:0048523
Term :negative regulation of cellular process
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
16AARSalanyl-tRNA synthetase
43ACHEacetylcholinesterase
87ACTN1actinin_ alpha 1
116ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
118ADD1adducin 1 (alpha)
156ADRBK1adrenergic_ beta_ receptor kinase 1
207AKT1v-akt murine thymoma viral oncogene homolog 1
331XIAPX-linked inhibitor of apoptosis
348APOEapolipoprotein E
387RHOAras homolog gene family_ member A
444ASPHaspartate beta-hydroxylase
498ATP5A1ATP synthase_ H+ transporting_ mitochondrial F1 complex_ alpha subunit 1_ cardiac muscle
506ATP5BATP synthase_ H+ transporting_ mitochondrial F1 complex_ beta polypeptide
573BAG1BCL2-associated athanogene
581BAXBCL2-associated X protein
596BCL2B-cell CLL/lymphoma 2
627BDNFbrain-derived neurotrophic factor
836CASP3caspase 3_ apoptosis-related cysteine peptidase
847CATcatalase
857CAV1caveolin 1_ caveolae protein_ 22kDa
858CAV2caveolin 2
859CAV3caveolin 3
1012CDH13cadherin 13_ H-cadherin (heart)
1020CDK5cyclin-dependent kinase 5
1072CFL1cofilin 1 (non-muscle)
1410CRYABcrystallin_ alpha B
1499CTNNB1catenin (cadherin-associated protein)_ beta 1_ 88kDa
1612DAPK1death-associated protein kinase 1
1741DLG3discs_ large homolog 3 (Drosophila)
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1827RCAN1regulator of calcineurin 1
1917EEF1A2eukaryotic translation elongation factor 1 alpha 2
2073ERCC5excision repair cross-complementing rodent repair deficiency_ complementation group 5
2247FGF2fibroblast growth factor 2 (basic)
2342FNTBFarnesyltransferase_ CAAX box_ beta
2444FRKfyn-related kinase
2495FTH1ferritin_ heavy polypeptide 1
2668GDNFglial cell derived neurotrophic factor
2810SFNstratifin
2909GRLF1glucocorticoid receptor DNA binding factor 1
2918GRM8glutamate receptor_ metabotropic 8
2931GSK3Aglycogen synthase kinase 3 alpha
2932GSK3Bglycogen synthase kinase 3 beta
2956MSH6mutS homolog 6 (E. coli)
3064HTThuntingtin
3065HDAC1histone deacetylase 1
3066HDAC2histone deacetylase 2
3084NRG1neuregulin 1
3146HMGB1high-mobility group box 1
3148HMGB2high-mobility group box 2
3162HMOX1heme oxygenase (decycling) 1
3299HSF4heat shock transcription factor 4
3309HSPA5heat shock 70kDa protein 5 (glucose-regulated protein_ 78kDa)
3313HSPA9heat shock 70kDa protein 9 (mortalin)
3315HSPB1heat shock 27kDa protein 1
3351HTR1B5-hydroxytryptamine (serotonin) receptor 1B
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C
3479IGF1insulin-like growth factor 1 (somatomedin C)
3570IL6Rinterleukin 6 receptor
3572IL6STinterleukin 6 signal transducer (gp130_ oncostatin M receptor)
3646EIF3Eeukaryotic translation initiation factor 3_ subunit E
3717JAK2Janus kinase 2
3725JUNjun proto-oncogene
3767KCNJ11potassium inwardly-rectifying channel_ subfamily J_ member 11
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4323MMP14matrix metallopeptidase 14 (membrane-inserted)
4436MSH2mutS homolog 2_ colon cancer_ nonpolyposis type 1 (E. coli)
4437MSH3mutS homolog 3 (E. coli)
4542MYO1Fmyosin IF
4671NAIPNLR family_ apoptosis inhibitory protein
4790NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
4803NGFnerve growth factor (beta polypeptide)
4842NOS1nitric oxide synthase 1 (neuronal)
4988OPRM1opioid receptor_ mu 1
5027p2rx7purinergic receptor P2X_ ligand-gated ion channel_ 7
5290PIK3CAphosphoinositide-3-kinase_ catalytic_ alpha polypeptide
5295PIK3R1phosphoinositide-3-kinase_ regulatory subunit 1 (alpha)
5296PIK3R2phosphoinositide-3-kinase_ regulatory subunit 2 (beta)
5300PIN1peptidylprolyl cis/trans isomerase_ NIMA-interacting 1
5467PPARDperoxisome proliferator-activated receptor delta
5468PPARGperoxisome proliferator-activated receptor gamma
5578PRKCAprotein kinase C_ alpha
5580PRKCDprotein kinase C_ delta
5590PRKCZProtein kinase C_ zeta
5594MAPK1mitogen-activated protein kinase 1
5599MAPK8mitogen-activated protein kinase 8
5621PRNPprion protein
5663PSEN1presenilin 1
5705PSMC5proteasome (prosome_ macropain) 26S subunit_ ATPase_ 5
5728PTENphosphatase and tensin homolog
5743PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
6093ROCK1Rho-associated_ coiled-coil containing protein kinase 1
6188RPS3ribosomal protein S3
6597SMARCA4SWI/SNF related_ matrix associated_ actin dependent regulator of chromatin_ subfamily a_ member 4
6601SMARCC2SWI/SNF related_ matrix associated_ actin dependent regulator of chromatin_ subfamily c_ member 2
6647SOD1superoxide dismutase 1_ soluble
6776STAT5Asignal transducer and activator of transcription 5A
6777STAT5Bsignal transducer and activator of transcription 5B
6812STXBP1syntaxin binding protein 1
6829SUPT5Hsuppressor of Ty 5 homolog (S. cerevisiae)
7068THRBthyroid hormone receptor_ beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2_ avian)
7078TIMP3TIMP metallopeptidase inhibitor 3
7099TLR4toll-like receptor 4
7157TP53tumor protein p53
7161TP73tumor protein p73
7248TSC1tuberous sclerosis 1
7249TSC2tuberous sclerosis 2
7251TSG101tumor susceptibility gene 101
7329UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog_ yeast)
7341SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
7376NR1H2nuclear receptor subfamily 1_ group H_ member 2
7422VEGFAvascular endothelial growth factor A
7531YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein_ epsilon polypeptide
7533YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein_ eta polypeptide
7534YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein_ zeta polypeptide
8408ULK1unc-51-like kinase 1 (C. elegans)
8453CUL2cullin 2
8454CUL1cullin 1
8520HAT1histone acetyltransferase 1
8539API5apoptosis inhibitor 5
8678BECN1Beclin 1_ autophagy related
8841HDAC3histone deacetylase 3
9241NOGnoggin
9531BAG3BCL2-associated athanogene 3
9536PTGESprostaglandin E synthase
9611NCOR1nuclear receptor corepressor 1
9759HDAC4histone deacetylase 4
9927MFN2mitofusin 2
10013HDAC6histone deacetylase 6
10014HDAC5histone deacetylase 5
10049DNAJB6DnaJ (Hsp40) homolog_ subfamily B_ member 6
10062NR1H3nuclear receptor subfamily 1_ group H_ member 3
10202DHRS2dehydrogenase/reductase (SDR family) member 2
11188NISCHnischarin
11252PACSIN2protein kinase C and casein kinase substrate in neurons 2
22933SIRT2sirtuin 2
22938SNW1SNW domain containing 1
23090ZNF423zinc finger protein 423
23408SIRT5sirtuin 5
23409SIRT4sirtuin 4
23410SIRT3sirtuin 3
23411SIRT1sirtuin 1
23560GTPBP4GTP binding protein 4
23636NUP62nucleoporin 62kDa
25825BACE2beta-site APP-cleaving enzyme 2
25920COBRA1cofactor of BRCA1
25942SIN3ASIN3 homolog A_ transcription regulator (yeast)
26173INTS1integrator complex subunit 1
27161EIF2C2Eukaryotic translation initiation factor 2C_ 2
27339PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
51160VPS28vacuolar protein sorting 28 homolog (S. cerevisiae)
51176LEF1lymphoid enhancer-binding factor 1
51497TH1LTH1-like (Drosophila)
51547SIRT7sirtuin 7
51548SIRT6sirtuin 6
51564HDAC7histone deacetylase 7
51616TAF9BTAF9B RNA polymerase II_ TATA box binding protein (TBP)-associated factor_ 31kDa
51701NLKnemo-like kinase
53827FXYD5FXYD domain containing ion transport regulator 5
55869HDAC8histone deacetylase 8
56033BARX1BARX homeobox 1
56848SPHK2sphingosine kinase 2
84447SYVN1synovial apoptosis inhibitor 1_ synoviolin
192683SCAMP5secretory carrier membrane protein 5