PFAM ID:GO:0004871
Term :signal transducer activity
Entrez Gene IDs are linked to their corresponding NCBI GenBank entry.
Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database.
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Entrez Gene IDApproved SymbolApproved Name
88ACTN2actinin_ alpha 2
117ADCYAP1R1adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
134ADORA1adenosine A1 receptor
135ADORA2Aadenosine A2a receptor
136ADORA2Badenosine A2b receptor
156ADRBK1adrenergic_ beta_ receptor kinase 1
157ADRBK2adrenergic_ beta_ receptor kinase 2
367ARandrogen receptor
573BAG1BCL2-associated athanogene
1020CDK5cyclin-dependent kinase 5
1128CHRM1cholinergic receptor_ muscarinic 1
1129CHRM2cholinergic receptor_ muscarinic 2
1131CHRM3cholinergic receptor_ muscarinic 3
1132CHRM4cholinergic receptor_ muscarinic 4
1133CHRM5cholinergic receptor_ muscarinic 5
1241LTB4Rleukotriene B4 receptor
1268CNR1Cannabinoid receptor 1 (brain)
1269CNR2cannabinoid receptor 2 (macrophage)
1387CREBBPCREB binding protein
1499CTNNB1catenin (cadherin-associated protein)_ beta 1_ 88kDa
1812DRD1dopamine receptor D1
1813DRD2dopamine receptor D2
1814DRD3dopamine receptor D3
1815DRD4dopamine receptor D4
1816DRD5dopamine receptor D5
1950EGFepidermal growth factor
2057EPORerythropoietin receptor
2209FCGR1AFc fragment of IgG_ high affinity Ia_ receptor (CD64)
2339FNTAfarnesyltransferase_ CAAX box_ alpha
2357FPR1formyl peptide receptor 1
2550GABBR1gamma-aminobutyric acid (GABA) B receptor_ 1
2554GABRA1gamma-aminobutyric acid (GABA) A receptor_ alpha 1
2566GABRG2gamma-aminobutyric acid (GABA) A receptor_ gamma 2
2674GFRA1GDNF family receptor alpha 1
2675GFRA2GDNF family receptor alpha 2
2676GFRA3GDNF family receptor alpha 3
2740GLP1Rglucagon-like peptide 1 receptor
2770GNAI1guanine nucleotide binding protein (G protein)_ alpha inhibiting activity polypeptide 1
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein)_ beta polypeptide 1
2798GNRHRgonadotropin-releasing hormone receptor
2826CCR10chemokine (C-C motif) receptor 10
2847MCHR1melanin-concentrating hormone receptor 1
2868GRK4G protein-coupled receptor kinase 4
2869GRK5G protein-coupled receptor kinase 5
2870GRK6G protein-coupled receptor kinase 6
2890GRIA1glutamate receptor_ ionotropic_ AMPA 1
2891GRIA2glutamate receptor_ ionotropic_ AMPA 2
2892GRIA3glutamate receptor_ ionotrophic_ AMPA 3
2893GRIA4glutamate receptor_ ionotrophic_ AMPA 4
2902GRIN1glutamate receptor_ ionotropic_ N-methyl D-aspartate 1
2903GRIN2Aglutamate receptor_ ionotropic_ N-methyl D-aspartate 2A
2904GRIN2Bglutamate receptor_ ionotropic_ N-methyl D-aspartate 2B
2905GRIN2Cglutamate receptor_ ionotropic_ N-methyl D-aspartate 2C
2906GRIN2Dglutamate receptor_ ionotropic_ N-methyl D-aspartate 2D
2911GRM1glutamate receptor_ metabotropic 1
2912GRM2glutamate receptor_ metabotropic 2
2913GRM3glutamate receptor_ metabotropic 3
2914GRM4glutamate receptor_ metabotropic 4
2915GRM5glutamate receptor_ metabotropic 5
2916GRM6glutamate receptor_ metabotropic 6
2917GRM7glutamate receptor_ metabotropic 7
2918GRM8glutamate receptor_ metabotropic 8
3061HCRTR1hypocretin (orexin) receptor 1
3062HCRTR2hypocretin (orexin) receptor 2
3084NRG1neuregulin 1
3091HIF1Ahypoxia inducible factor 1_ alpha subunit (basic helix-loop-helix transcription factor)
3162HMOX1heme oxygenase (decycling) 1
3350HTR1A5-hydroxytryptamine (serotonin) receptor 1A
3351HTR1B5-hydroxytryptamine (serotonin) receptor 1B
3355HTR1F5-hydroxytryptamine (serotonin) receptor 1F
3358HTR2C5-hydroxytryptamine (serotonin) receptor 2C
3362HTR65-hydroxytryptamine (serotonin) receptor 6
3363HTR75-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
3570IL6Rinterleukin 6 receptor
3572IL6STinterleukin 6 signal transducer (gp130_ oncostatin M receptor)
3643INSRinsulin receptor
3654IRAK1interleukin-1 receptor-associated kinase 1
3674ITGA2Bintegrin_ alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex_ antigen CD41)
3708ITPR1inositol 1_4_5-triphosphate receptor_ type 1
3709ITPR2inositol 1_4_5-triphosphate receptor_ type 2
3710ITPR3inositol 1_4_5-triphosphate receptor_ type 3
3716JAK1Janus kinase 1
3717JAK2Janus kinase 2
3718JAK3Janus kinase 3
3791KDRkinase insert domain receptor (a type III receptor tyrosine kinase)
3921RPSAribosomal protein SA
3977LIFRleukemia inhibitory factor receptor alpha
4214MAP3K1mitogen-activated protein kinase kinase kinase 1
4217MAP3K5mitogen-activated protein kinase kinase kinase 5
4293MAP3K9mitogen-activated protein kinase kinase kinase 9
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4296MAP3K11mitogen-activated protein kinase kinase kinase 11
4803NGFnerve growth factor (beta polypeptide)
4852NPYneuropeptide Y
4914NTRK1neurotrophic tyrosine kinase_ receptor_ type 1
4916NTRK3neurotrophic tyrosine kinase_ receptor_ type 3
4985OPRD1opioid receptor_ delta 1
4986OPRK1opioid receptor_ kappa 1
4987OPRL1opiate receptor-like 1
4988OPRM1opioid receptor_ mu 1
5023P2RX1purinergic receptor P2X_ ligand-gated ion channel_ 1
5024P2RX3purinergic receptor P2X_ ligand-gated ion channel_ 3
5025P2RX4purinergic receptor P2X_ ligand-gated ion channel_ 4
5026P2RX5purinergic receptor P2X_ ligand-gated ion channel_ 5
5027p2rx7purinergic receptor P2X_ ligand-gated ion channel_ 7
5028P2RY1purinergic receptor P2Y_ G-protein coupled_ 1
5029P2RY2purinergic receptor P2Y_ G-protein coupled_ 2
5030P2RY4pyrimidinergic receptor P2Y_ G-protein coupled_ 4
5031P2RY6pyrimidinergic receptor P2Y_ G-protein coupled_ 6
5032P2RY11purinergic receptor P2Y_ G-protein coupled_ 11
5347PLK1polo-like kinase 1
5356PLRG1pleiotropic regulator 1 (PRL1 homolog_ Arabidopsis)
5467PPARDperoxisome proliferator-activated receptor delta
5468PPARGperoxisome proliferator-activated receptor gamma
5581PRKCEprotein kinase C_ epsilon
5594MAPK1mitogen-activated protein kinase 1
5595MAPK3mitogen-activated protein kinase 3
5599MAPK8mitogen-activated protein kinase 8
5601MAPK9mitogen-activated protein kinase 9
5602MAPK10mitogen-activated protein kinase 10
5604MAP2K1mitogen-activated protein kinase kinase 1
5727PTCH1patched 1
6011GRK1G protein-coupled receptor kinase 1
6096RORBRAR-related orphan receptor B
6256RXRAretinoid X receptor_ alpha
6257RXRBretinoid X receptor_ beta
6258RXRGretinoid X receptor_ gamma
6352CCL5chemokine (C-C motif) ligand 5
6575SLC20A2solute carrier family 20 (phosphate transporter)_ member 2
6653SORL1sortilin-related receptor_ L(DLR class) A repeats-containing
6714SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
6776STAT5Asignal transducer and activator of transcription 5A
6777STAT5Bsignal transducer and activator of transcription 5B
7067THRAthyroid hormone receptor_ alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog_ avian)
7068THRBthyroid hormone receptor_ beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2_ avian)
7099TLR4toll-like receptor 4
7188TRAF5TNF receptor-associated factor 5
7376NR1H2nuclear receptor subfamily 1_ group H_ member 2
7855FZD5frizzled homolog 5 (Drosophila)
8517IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells_ kinase gamma
8622PDE8Bphosphodiesterase 8B
8660IRS2insulin receptor substrate 2
8767RIPK2receptor-interacting serine-threonine kinase 2
8797TNFRSF10Atumor necrosis factor receptor superfamily_ member 10a
9038TAAR5trace amine associated receptor 5
9049AIParyl hydrocarbon receptor interacting protein
9287TAAR2trace amine associated receptor 2
9288TAAR3trace amine associated receptor 3 (gene/pseudogene)
9572NR1D1nuclear receptor subfamily 1_ group D_ member 1
9934P2RY14purinergic receptor P2Y_ G-protein coupled_ 14
9993DGCR2DiGeorge syndrome critical region gene 2
10062NR1H3nuclear receptor subfamily 1_ group H_ member 3
10342TFGTRK-fused gene
10682EBPemopamil binding protein (sterol isomerase)
11188NISCHnischarin
22953P2RX2purinergic receptor P2X_ ligand-gated ion channel_ 2
23390ZDHHC17zinc finger_ DHHC-type containing 17
50618ITSN2intersectin 2
51196PLCE1Phospholipase C_ epsilon 1
51701NLKnemo-like kinase
53829P2RY13purinergic receptor P2Y_ G-protein coupled_ 13
54503ZDHHC13zinc finger_ DHHC-type containing 13
56993TOMM22translocase of outer mitochondrial membrane 22 homolog (yeast)
64096GFRA4GDNF family receptor alpha 4
64699TMPRSS3transmembrane protease_ serine 3
64805P2RY12purinergic receptor P2Y_ G-protein coupled_ 12
83551TAAR8trace amine associated receptor 8
84539MCHR2melanin-concentrating hormone receptor 2
116443GRIN3Aglutamate receptor_ ionotropic_ N-methyl-D-aspartate 3A
116444GRIN3Bglutamate receptor_ ionotropic_ N-methyl-D-aspartate 3B
131890GRK7G protein-coupled receptor kinase 7
133522PPARGC1Bperoxisome proliferator-activated receptor gamma_ coactivator 1 beta
134860TAAR9trace amine associated receptor 9 (gene/pseudogene)
134864TAAR1trace amine associated receptor 1
266743NPAS4neuronal PAS domain protein 4
286530P2RY8purinergic receptor P2Y_ G-protein coupled_ 8
319100TAAR6trace amine associated receptor 6
389840MAP3K15Mitogen-activated protein kinase kinase kinase 15