GO ID:0003824
Term :catalytic activity

Entrez Gene IDs are linked to their corresponding NCBI GenBank entry. Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database. Note that a login is required for the HD Research CrossRoads database.

Entrez Gene IDApproved SymbolApproved Name
16AARSalanyl-tRNA synthetase
31ACACAacetyl-CoA carboxylase alpha
38ACAT1acetyl-CoA acetyltransferase 1
107ADCY1adenylate cyclase 1 (brain)
191AHCYadenosylhomocysteinase
207AKT1v-akt murine thymoma viral oncogene homolog 1
208AKT2v-akt murine thymoma viral oncogene homolog 2
226ALDOAaldolase A, fructose-bisphosphate
249ALPLalkaline phosphatase, liver/bone/kidney
331XIAPX-linked inhibitor of apoptosis
378ARF4ADP-ribosylation factor 4
444ASPHaspartate beta-hydroxylase
476ATP1A1ATPase, Na+/K+ transporting, alpha 1 polypeptide
498ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
506ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
513ATP5DATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
515ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
523ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
525ATP6V1B1ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
529ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
538ATP7AATPase, Cu++ transporting, alpha polypeptide
701BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)
726CAPN5calpain 5
759CA1carbonic anhydrase I
823CAPN1calpain 1, (mu/I) large subunit
824CAPN2calpain 2, (m/II) large subunit
834CASP1caspase 1, apoptosis-related cysteine peptidase
835CASP2caspase 2, apoptosis-related cysteine peptidase
836CASP3caspase 3, apoptosis-related cysteine peptidase
839CASP6caspase 6, apoptosis-related cysteine peptidase
840CASP7caspase 7, apoptosis-related cysteine peptidase
847CATcatalase
1020CDK5cyclin-dependent kinase 5
1147CHUKconserved helix-loop-helix ubiquitous kinase
1345COX6Ccytochrome c oxidase subunit VIc
1374CPT1Acarnitine palmitoyltransferase 1A (liver)
1387CREBBPCREB binding protein
1431CScitrate synthase
1457CSNK2A1casein kinase 2, alpha 1 polypeptide
1460CSNK2Bcasein kinase 2, beta polypeptide
1509CTSDcathepsin D
1514CTSL1cathepsin L1
1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 1
1659DHX8DEAH (Asp-Glu-Ala-His) box polypeptide 8
1759DNM1dynamin 1
1778DYNC1H1dynein, cytoplasmic 1, heavy chain 1
1781DYNC1I2dynein, cytoplasmic 1, intermediate chain 2
1785DNM2dynamin 2
1849DUSP7dual specificity phosphatase 7
1917EEF1A2eukaryotic translation elongation factor 1 alpha 2
1938EEF2eukaryotic translation elongation factor 2
1968EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
1983EIF5eukaryotic translation initiation factor 5
2071ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3
2073ERCC5excision repair cross-complementing rodent repair deficiency, complementation group 5
2184FAHfumarylacetoacetate hydrolase (fumarylacetoacetase)
2339FNTAfarnesyltransferase, CAAX box, alpha
2342FNTBfarnesyltransferase, CAAX box, beta
2444FRKfyn-related kinase
2475MTORmechanistic target of rapamycin (serine/threonine kinase)
2547XRCC6X-ray repair complementing defective repair in Chinese hamster cells 6
2597GAPDHglyceraldehyde-3-phosphate dehydrogenase
2648KAT2AK(lysine) acetyltransferase 2A
2770GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
2805GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
2819GPD1glycerol-3-phosphate dehydrogenase 1 (soluble)
2821GPIglucose-6-phosphate isomerase
2932GSK3Bglycogen synthase kinase 3 beta
2935GSPT1G1 to S phase transition 1
3065HDAC1histone deacetylase 1
3066HDAC2histone deacetylase 2
3093UBE2Kubiquitin-conjugating enzyme E2K
3156HMGCR3-hydroxy-3-methylglutaryl-CoA reductase
3157HMGCS13-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
3312HSPA8heat shock 70kDa protein 8
3551IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
3612IMPA1inositol(myo)-1(or 4)-monophosphatase 1
3654IRAK1interleukin-1 receptor-associated kinase 1
3706ITPKAinositol-trisphosphate 3-kinase A
3799KIF5Bkinesin family member 5B
3818KLKB1kallikrein B, plasma (Fletcher factor) 1
3832KIF11kinesin family member 11
4023LPLlipoprotein lipase
4214MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
4217MAP3K5mitogen-activated protein kinase kinase kinase 5
4255MGMTO-6-methylguanine-DNA methyltransferase
4293MAP3K9mitogen-activated protein kinase kinase kinase 9
4294MAP3K10mitogen-activated protein kinase kinase kinase 10
4296MAP3K11mitogen-activated protein kinase kinase kinase 11
4319MMP10matrix metallopeptidase 10 (stromelysin 2)
4323MMP14matrix metallopeptidase 14 (membrane-inserted)
4351MPImannose phosphate isomerase
4436MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
4521NUDT1nudix (nucleoside diphosphate linked moiety X)-type motif 1
4628MYH10myosin, heavy chain 10, non-muscle
4716NDUFB10NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
4723NDUFV1NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
4842NOS1nitric oxide synthase 1 (neuronal)
4905NSFN-ethylmaleimide-sensitive factor
4968OGG18-oxoguanine DNA glycosylase
5058PAK1p21 protein (Cdc42/Rac)-activated kinase 1
5062PAK2p21 protein (Cdc42/Rac)-activated kinase 2
5071PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
5136PDE1Aphosphodiesterase 1A, calmodulin-dependent
5138PDE2Aphosphodiesterase 2A, cGMP-stimulated
5141PDE4Aphosphodiesterase 4A, cAMP-specific
5142PDE4Bphosphodiesterase 4B, cAMP-specific
5144PDE4Dphosphodiesterase 4D, cAMP-specific
5160PDHA1pyruvate dehydrogenase (lipoamide) alpha 1
5190PEX6peroxisomal biogenesis factor 6
5213PFKMphosphofructokinase, muscle
5230PGK1phosphoglycerate kinase 1
5286PIK3C2Aphosphoinositide-3-kinase, class 2, alpha polypeptide
5289PIK3C3phosphoinositide-3-kinase, class 3
5290PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide
5291PIK3CBphosphoinositide-3-kinase, catalytic, beta polypeptide
5300PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 1
5315PKM2pyruvate kinase, muscle
5347PLK1polo-like kinase 1
5430POLR2Apolymerase (RNA) II (DNA directed) polypeptide A, 220kDa
5431POLR2Bpolymerase (RNA) II (DNA directed) polypeptide B, 140kDa
5495PPM1Bprotein phosphatase, Mg2+/Mn2+ dependent, 1B
5530PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme
5534PPP3R1protein phosphatase 3, regulatory subunit B, alpha
5557PRIM1primase, DNA, polypeptide 1 (49kDa)
5566PRKACAprotein kinase, cAMP-dependent, catalytic, alpha
5579PRKCBprotein kinase C, beta
5586PKN2protein kinase N2
5599MAPK8mitogen-activated protein kinase 8
5601MAPK9mitogen-activated protein kinase 9
5602MAPK10mitogen-activated protein kinase 10
5604MAP2K1mitogen-activated protein kinase kinase 1
5606MAP2K3mitogen-activated protein kinase kinase 3
5608MAP2K6mitogen-activated protein kinase kinase 6
5655KLK10kallikrein-related peptidase 10
5682PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
5686PSMA5proteasome (prosome, macropain) subunit, alpha type, 5
5688PSMA7proteasome (prosome, macropain) subunit, alpha type, 7
5690PSMB2proteasome (prosome, macropain) subunit, beta type, 2
5691PSMB3proteasome (prosome, macropain) subunit, beta type, 3
5693PSMB5proteasome (prosome, macropain) subunit, beta type, 5
5694PSMB6proteasome (prosome, macropain) subunit, beta type, 6
5695PSMB7proteasome (prosome, macropain) subunit, beta type, 7
5701PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 2
5702PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 3
5705PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 5
5706PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 6
5728PTENphosphatase and tensin homolog
5743PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
5861RAB1ARAB1A, member RAS oncogene family
5868RAB5ARAB5A, member RAS oncogene family
5901RANRAN, member RAS oncogene family
5903RANBP2RAN binding protein 2
5976UPF1UPF1 regulator of nonsense transcripts homolog (yeast)
6009RHEBRas homolog enriched in brain
6093ROCK1Rho-associated, coiled-coil containing protein kinase 1
6188RPS3ribosomal protein S3
6199RPS6KB2ribosomal protein S6 kinase, 70kDa, polypeptide 2
6389SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)
6390SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)
6416MAP2K4mitogen-activated protein kinase kinase 4
6477SIAH1siah E3 ubiquitin protein ligase 1
6597SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
6647SOD1superoxide dismutase 1, soluble
7052TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
7204TRIOtriple functional domain (PTPRF interacting)
7251TSG101tumor susceptibility gene 101
7317UBA1ubiquitin-like modifier activating enzyme 1
7319UBE2Aubiquitin-conjugating enzyme E2A
7322UBE2D2ubiquitin-conjugating enzyme E2D 2
7323UBE2D3ubiquitin-conjugating enzyme E2D 3
7328UBE2Hubiquitin-conjugating enzyme E2H
7329UBE2Iubiquitin-conjugating enzyme E2I
7334UBE2Nubiquitin-conjugating enzyme E2N
7336UBE2V2ubiquitin-conjugating enzyme E2 variant 2
7337UBE3Aubiquitin protein ligase E3A
7345UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
7347UCHL3ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
7353UFD1Lubiquitin fusion degradation 1 like (yeast)
7381UQCRBubiquinol-cytochrome c reductase binding protein
7415VCPvalosin containing protein
7846TUBA1Atubulin, alpha 1a
7919BAT1DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
8239USP9Xubiquitin specific peptidase 9, X-linked
8288EPXeosinophil peroxidase
8295TRRAPtransformation/transcription domain-associated protein
8408ULK1unc-51-like kinase 1 (C. elegans)
8510MMP23Bmatrix metallopeptidase 23B
8564KMOkynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
8622PDE8Bphosphodiesterase 8B
8644AKR1C3aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
8721EDF1endothelial differentiation-related factor 1
8766RAB11ARAB11A, member RAS oncogene family
8767RIPK2receptor-interacting serine-threonine kinase 2
8841HDAC3histone deacetylase 3
8851CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)
8867SYNJ1synaptojanin 1
8898MTMR2myotubularin related protein 2
8945BTRCbeta-transducin repeat containing E3 ubiquitin protein ligase
9126SMC3structural maintenance of chromosomes 3
9230RAB11BRAB11B, member RAS oncogene family
9252RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
9343EFTUD2elongation factor Tu GTP binding domain containing 2
9429ABCG2ATP-binding cassette, sub-family G (WHITE), member 2
9475ROCK2Rho-associated, coiled-coil containing protein kinase 2
9525VPS4Bvacuolar protein sorting 4 homolog B (S. cerevisiae)
9536PTGESprostaglandin E synthase
9582APOBEC3Bapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
9734HDAC9histone deacetylase 9
9759HDAC4histone deacetylase 4
9927MFN2mitofusin 2
10013HDAC6histone deacetylase 6
10054UBA2ubiquitin-like modifier activating enzyme 2
10055SAE1SUMO1 activating enzyme subunit 1
10056FARSBphenylalanyl-tRNA synthetase, beta subunit
10059DNM1Ldynamin 1-like
10171RCL1RNA terminal phosphate cyclase-like 1
10202DHRS2dehydrogenase/reductase (SDR family) member 2
10212DDX39DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
10213PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
10262SF3B4splicing factor 3b, subunit 4, 49kDa
10273STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
10383TUBB2Ctubulin, beta 4B class IVb
10476ATP5HATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
10533ATG7autophagy related 7
10558SPTLC1serine palmitoyltransferase, long chain base subunit 1
10569SLU7SLU7 splicing factor homolog (S. cerevisiae)
10594PRPF8PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
10682EBPemopamil binding protein (sterol isomerase)
10939AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
10946SF3A3splicing factor 3a, subunit 3, 60kDa
11012KLK11kallikrein-related peptidase 11
22858ICKintestinal cell (MAK-like) kinase
22929SEPHS1selenophosphate synthetase 1
22933SIRT2sirtuin 2
23020SNRNP200small nuclear ribonucleoprotein 200kDa (U5)
23049SMG1smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
23077MYCBP2MYC binding protein 2, E3 ubiquitin protein ligase
23390ZDHHC17zinc finger, DHHC-type containing 17
23409SIRT4sirtuin 4
23411SIRT1sirtuin 1
23450SF3B3splicing factor 3b, subunit 3, 130kDa
23451SF3B1splicing factor 3b, subunit 1, 155kDa
23483TGDSTDP-glucose 4,6-dehydratase
23517SKIV2L2superkiller viralicidic activity 2-like 2 (S. cerevisiae)
23551RASD2RASD family, member 2
23560GTPBP4GTP binding protein 4
23604DAPK2death-associated protein kinase 2
23636NUP62nucleoporin 62kDa
25788RAD54BRAD54 homolog B (S. cerevisiae)
25825BACE2beta-site APP-cleaving enzyme 2
26260FBXO25F-box protein 25
26353HSPB8heat shock 22kDa protein 8
26750RPS6KC1ribosomal protein S6 kinase, 52kDa, polypeptide 1
27161EIF2C2eukaryotic translation initiation factor 2C, 2
27183VPS4Avacuolar protein sorting 4 homolog A (S. cerevisiae)
27339PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
27429HTRA2HtrA serine peptidase 2
28972SPCS1signal peptidase complex subunit 1 homolog (S. cerevisiae)
29959NRBP1nuclear receptor binding protein 1
50506DUOX2dual oxidase 2
51144HSD17B12hydroxysteroid (17-beta) dehydrogenase 12
51196PLCE1phospholipase C, epsilon 1
51606ATP6V1HATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
51692CPSF3cleavage and polyadenylation specific factor 3, 73kDa
51701NLKnemo-like kinase
51706CYB5R1cytochrome b5 reductase 1
53981CPSF2cleavage and polyadenylation specific factor 2, 100kDa
54503ZDHHC13zinc finger, DHHC-type containing 13
54583EGLN1egl nine homolog 1 (C. elegans)
54973CPSF3Lcleavage and polyadenylation specific factor 3-like
55589BMP2KBMP2 inducible kinase
56257MEPCEmethylphosphate capping enzyme
56848SPHK2sphingosine kinase 2
57455REXO1REX1, RNA exonuclease 1 homolog (S. cerevisiae)
57551TAOK1TAO kinase 1
59084ENPP5ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
59343SENP2SUMO1/sentrin/SMT3 specific peptidase 2
60559SPCS3signal peptidase complex subunit 3 homolog (S. cerevisiae)
64699TMPRSS3transmembrane protease, serine 3
81570CLPBClpB caseinolytic peptidase B homolog (E. coli)
83442SH3BGRL3SH3 domain binding glutamic acid-rich protein like 3
83657DYNLRB2dynein, light chain, roadblock-type 2
84447SYVN1synovial apoptosis inhibitor 1, synoviolin
114769CARD16caspase recruitment domain family, member 16
115426UHRF2ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
139596UPRTuracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
203068TUBBtubulin, beta class I
284086NEK8NIMA (never in mitosis gene a)- related kinase 8