GO ID:0016787
Term :hydrolase activity

Entrez Gene IDs are linked to their corresponding NCBI GenBank entry. Gene symbols are linked to the entry for the gene in the HD Research CrossRoads database. Note that a login is required for the HD Research CrossRoads database.

Entrez Gene IDApproved SymbolApproved Name
191AHCYadenosylhomocysteinase
249ALPLalkaline phosphatase, liver/bone/kidney
378ARF4ADP-ribosylation factor 4
476ATP1A1ATPase, Na+/K+ transporting, alpha 1 polypeptide
498ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
506ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
513ATP5DATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
515ATP5F1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
523ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
525ATP6V1B1ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
529ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
538ATP7AATPase, Cu++ transporting, alpha polypeptide
726CAPN5calpain 5
823CAPN1calpain 1, (mu/I) large subunit
824CAPN2calpain 2, (m/II) large subunit
834CASP1caspase 1, apoptosis-related cysteine peptidase
835CASP2caspase 2, apoptosis-related cysteine peptidase
836CASP3caspase 3, apoptosis-related cysteine peptidase
839CASP6caspase 6, apoptosis-related cysteine peptidase
840CASP7caspase 7, apoptosis-related cysteine peptidase
847CATcatalase
1509CTSDcathepsin D
1514CTSL1cathepsin L1
1636ACEangiotensin I converting enzyme (peptidyl-dipeptidase A) 1
1659DHX8DEAH (Asp-Glu-Ala-His) box polypeptide 8
1759DNM1dynamin 1
1778DYNC1H1dynein, cytoplasmic 1, heavy chain 1
1781DYNC1I2dynein, cytoplasmic 1, intermediate chain 2
1785DNM2dynamin 2
1849DUSP7dual specificity phosphatase 7
1917EEF1A2eukaryotic translation elongation factor 1 alpha 2
1938EEF2eukaryotic translation elongation factor 2
1968EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
1983EIF5eukaryotic translation initiation factor 5
2071ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3
2073ERCC5excision repair cross-complementing rodent repair deficiency, complementation group 5
2184FAHfumarylacetoacetate hydrolase (fumarylacetoacetase)
2547XRCC6X-ray repair complementing defective repair in Chinese hamster cells 6
2770GNAI1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
2778GNASGNAS complex locus
2782GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
2935GSPT1G1 to S phase transition 1
3065HDAC1histone deacetylase 1
3066HDAC2histone deacetylase 2
3312HSPA8heat shock 70kDa protein 8
3612IMPA1inositol(myo)-1(or 4)-monophosphatase 1
3799KIF5Bkinesin family member 5B
3818KLKB1kallikrein B, plasma (Fletcher factor) 1
3832KIF11kinesin family member 11
4023LPLlipoprotein lipase
4319MMP10matrix metallopeptidase 10 (stromelysin 2)
4323MMP14matrix metallopeptidase 14 (membrane-inserted)
4436MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
4521NUDT1nudix (nucleoside diphosphate linked moiety X)-type motif 1
4628MYH10myosin, heavy chain 10, non-muscle
4905NSFN-ethylmaleimide-sensitive factor
4968OGG18-oxoguanine DNA glycosylase
5136PDE1Aphosphodiesterase 1A, calmodulin-dependent
5138PDE2Aphosphodiesterase 2A, cGMP-stimulated
5141PDE4Aphosphodiesterase 4A, cAMP-specific
5142PDE4Bphosphodiesterase 4B, cAMP-specific
5144PDE4Dphosphodiesterase 4D, cAMP-specific
5190PEX6peroxisomal biogenesis factor 6
5495PPM1Bprotein phosphatase, Mg2+/Mn2+ dependent, 1B
5530PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme
5534PPP3R1protein phosphatase 3, regulatory subunit B, alpha
5604MAP2K1mitogen-activated protein kinase kinase 1
5655KLK10kallikrein-related peptidase 10
5682PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
5686PSMA5proteasome (prosome, macropain) subunit, alpha type, 5
5688PSMA7proteasome (prosome, macropain) subunit, alpha type, 7
5690PSMB2proteasome (prosome, macropain) subunit, beta type, 2
5691PSMB3proteasome (prosome, macropain) subunit, beta type, 3
5693PSMB5proteasome (prosome, macropain) subunit, beta type, 5
5694PSMB6proteasome (prosome, macropain) subunit, beta type, 6
5695PSMB7proteasome (prosome, macropain) subunit, beta type, 7
5701PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 2
5702PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 3
5705PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 5
5706PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 6
5728PTENphosphatase and tensin homolog
5861RAB1ARAB1A, member RAS oncogene family
5868RAB5ARAB5A, member RAS oncogene family
5901RANRAN, member RAS oncogene family
5976UPF1UPF1 regulator of nonsense transcripts homolog (yeast)
6009RHEBRas homolog enriched in brain
6188RPS3ribosomal protein S3
6597SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
7345UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
7347UCHL3ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
7353UFD1Lubiquitin fusion degradation 1 like (yeast)
7415VCPvalosin containing protein
7846TUBA1Atubulin, alpha 1a
7919BAT1DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
8239USP9Xubiquitin specific peptidase 9, X-linked
8510MMP23Bmatrix metallopeptidase 23B
8622PDE8Bphosphodiesterase 8B
8766RAB11ARAB11A, member RAS oncogene family
8841HDAC3histone deacetylase 3
8867SYNJ1synaptojanin 1
8898MTMR2myotubularin related protein 2
9126SMC3structural maintenance of chromosomes 3
9230RAB11BRAB11B, member RAS oncogene family
9343EFTUD2elongation factor Tu GTP binding domain containing 2
9429ABCG2ATP-binding cassette, sub-family G (WHITE), member 2
9525VPS4Bvacuolar protein sorting 4 homolog B (S. cerevisiae)
9582APOBEC3Bapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
9734HDAC9histone deacetylase 9
9759HDAC4histone deacetylase 4
9927MFN2mitofusin 2
10013HDAC6histone deacetylase 6
10059DNM1Ldynamin 1-like
10212DDX39DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
10213PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
10383TUBB2Ctubulin, beta 4B class IVb
10476ATP5HATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
10939AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
11012KLK11kallikrein-related peptidase 11
22933SIRT2sirtuin 2
23020SNRNP200small nuclear ribonucleoprotein 200kDa (U5)
23409SIRT4sirtuin 4
23411SIRT1sirtuin 1
23517SKIV2L2superkiller viralicidic activity 2-like 2 (S. cerevisiae)
23551RASD2RASD family, member 2
23560GTPBP4GTP binding protein 4
25788RAD54BRAD54 homolog B (S. cerevisiae)
25825BACE2beta-site APP-cleaving enzyme 2
27161EIF2C2eukaryotic translation initiation factor 2C, 2
27183VPS4Avacuolar protein sorting 4 homolog A (S. cerevisiae)
27429HTRA2HtrA serine peptidase 2
28972SPCS1signal peptidase complex subunit 1 homolog (S. cerevisiae)
51196PLCE1phospholipase C, epsilon 1
51606ATP6V1HATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
51692CPSF3cleavage and polyadenylation specific factor 3, 73kDa
53981CPSF2cleavage and polyadenylation specific factor 2, 100kDa
54973CPSF3Lcleavage and polyadenylation specific factor 3-like
57455REXO1REX1, RNA exonuclease 1 homolog (S. cerevisiae)
59084ENPP5ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
59343SENP2SUMO1/sentrin/SMT3 specific peptidase 2
60559SPCS3signal peptidase complex subunit 3 homolog (S. cerevisiae)
64699TMPRSS3transmembrane protease, serine 3
81570CLPBClpB caseinolytic peptidase B homolog (E. coli)
83657DYNLRB2dynein, light chain, roadblock-type 2
114769CARD16caspase recruitment domain family, member 16
203068TUBBtubulin, beta class I