Susana Machado (Msc.) - Researcher

Centre for Molecular and Structural Biomedicine (CBME)

Faculty of Sciences and Technology (building 8)

University of Algarve

Phone: + 351 289 800 100 (extn. 7177)

Academic Degrees

2011: Msc. degree in Biomedical Sciences, University of Algarve, Faro, Portugal.
2007: Licenciate degree (pre-Bologna) in Biochemistry, University of Algarve, Faro, Portugal

Positions

2014-present: Researcher at Systems Biology and Bioinformatics Group, CBME & CCMAR, University of Algarve, Faro, Portugal
2014: Research Consultant at Michael Pungente's Group, Weill Cornell Medical College, Doha, Qatar
2011-2014: Researcher at Gene Therapy Group, CBME, University of Algarve, Faro, Portugal
2011: Biomedical Sciences MSc Research Project: Development of polymer-based delivery systems for the delivery of fusogenic factors, University of Algarve, Faro, Portugal
2007: Biochemistry Licenciate Research Project: Origin of Fucus vesiculosus in Ria Formosa, CCMAR, Faro, Portugal

Publications

Machado, S., Raju, L. and Pungente, M.D. (2015) Gene Transfer Potential of a Lipofuscin Fluorophore, A2E. Materials Today: Proceedings, 2, 331-335 (pdf)

Kalathur, R., Giner-Lamia, J., Machado, S., Ayasolla, K. and Futschik, M. (2015) The unfolded protein response and its potential role in Huntingtons disease elucidated by a systems biology approach. F1000 Research.(html+pdf)

Pinto, J.P., Kalathur, R.K., Oliveira, D.V., Barata, T., Machado, R.S., Machado, S., Pacheco-Leyva, I., Duarte, I. and Futschik, M.E. (2015) StemChecker: a web-based tool to discover and explore stemness signatures in gene sets.Nucleic acids research.43 (W1): W72-W77 (pdf + html)

Machado S, Calado SM, Bitoque D, Oliveira AV, Ã˜pstad C, Zeeshan M, Sliwka H, Partali V, Pungente MD, Silva GA. Cationic Polyene Phospholipids as DNA Carriers for Ocular Gene Therapy, Biomed Research International, vol. 2014, Article ID 703253, 13 pages, 2014 (pdf)

Calado SM, Oliveira AV, Machado S, Haase R, Silva GA. Sustained Gene Expression in the Retina by improved Episomal Vectors, Tissue Engineering Part A, doi:10.1089/ten.tea.2013.0672, 2014. (pdf)

Bitoque D, Oliveira AV, Machado S, Lopes E, Duran M, Rosa da Costa A, Silva GA. Efficiency of RAFT-synthesized PDMAEMA in gene transfer to the retina, Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/term.1909, 2014. (pdf)

Presentations

S Machado, R Kalathur, DV Oliveira, T Barata, R Machado, I Pacheco-Leyva, I Duarte, M Futschik, J Pinto (2015) StemChecker: a web-based tool to discover and explore stemness signatures in gene sets.9th International Meeting of the Portuguese society for Stem cells and Cell therapies. Oeiras. Portugal.

DV Oliveira, I Duarte, RS Machado, I Pacheco-Leyva, T Justo, JP Pinto, S Machado, JA Belo, J Bragança & ME Futschik (2015) From Stem Cells 2 Heart: Finding novel candidate isoforms and genes for cardiomyogenesis. 9th International Meeting of the Portuguese society for Stem cells and Cell therapies. Oeiras. Portugal.

RS Machado, JP Pinto, DV Oliveira, I. Duarte, S Machado, J Bragança & M Futschik (2015) A meta-analysis study of stem cell differentiation in the context of cardiogenesis.9th International Meeting of the Portuguese society for Stem cells and Cell therapies. Oeiras. Portugal.

Machado S, SimÃ£o S, Ã˜pstad C, Sliwka HR, Partali V, Pungente M, Silva GA. Carotenoidbased lipoplexes efficiently transfect retinal pigment epithelium cells, Poster presented at: ESGCT and SETGyC Collaborative Congress, Madrid, Spain, 25-28 October 2013

Bitoque D, SimÃ£o S, Calado S, Machado S, Afonso C, Oliveira AV, Silva GA. Hybrid strategies for retinal gene delivery, Poster presented at: 8th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies; Faro, Portugal, 9-10 May 2013.

Machado S, Calado SM, Oliveira AV, Jorge S, Christer L. Ã˜pstad, Hans-Richard Sliwka, Vassilia Partali, Pungente M, Silva GA. Novel carotenoid lipid vectors for ocular gene therapy, Poster presented at: XXth Annual ESGCT/FSCGT Collaborative Congress; Paris, France; 25- 29 October 2012.

Machado S, Calado SM., Santos MI., Alvarez-Dolado M., Silva GA. Nanoparticles for controlled release of therapeutic molecules after stroke. Poster presented at: World Conference of Regenerative Medicine; Leipzig, Germany; 2-4 November 2011.

Calado SM, Oliveira AV, Silva AP, Machado S, Haase R, Silva GA. Evaluation of a new plasmid-based expression systems for gene transfer to the retina. Poster presented at: XIXth Annual ESGCT/BSGT Collaborative Congress; Brighton; UK; 27-31 October 2011.

Technical courses

Qualification to perform animal experimentation on rodents, fish and amphibian in scientific research, category B, in accordance to the European guidelines of FELASA.

Supervision of Students

Michael Xufre. Evaluation of novel cationic lipids as vectors for gene therapy. University of Algarve, 2013 (Research thesis in BSc Biomedical Sciences, University Algarve)

Laura ColaÃ§o. Evaluation of the stability profile of nanoparticles for controlled release of therapeutic molecules. University of Algarve, 2012 (Research thesis in BSc Biomedical Sciences, University Algarve)

Pedro Rouxinol. Gene therapy: Liposomes as vectors. University of Algarve, 2012 (MEE student in Medicine Course)

Links

My Google Scholar profile