KEGG Pathways enriched in HD-relevant genes

KEGG IDs are linked to the KEGG website (http://www.genome.jp). The list of HD-relevant genes for each category can be found following the links provided in the Term column.

KEGGID P-Value FDR Odds Ratio Expected Count Count Total number Term
4080 1.42E-18 2.43E-16 3.92 29.32 80 256 Neuroactive ligand-receptor interaction
4210 9.14E-13 7.82E-11 5.64 10.07 36 88 Apoptosis
5016 4.54E-12 2.59E-10 3.63 19.92 53 174 Huntington's disease
5014 2.83E-11 1.21E-09 7.21 6.29 26 55 Amyotrophic lateral sclerosis (ALS)
4020 3.13E-10 1.07E-08 3.26 20.15 50 176 Calcium signaling pathway
3010 1.14E-09 3.25E-08 4.63 9.73 31 85 Ribosome
4722 1.62E-09 3.95E-08 3.69 14.31 39 125 Neurotrophin signaling pathway
4720 3.32E-09 7.10E-08 5.04 8.01 27 70 Long-term potentiation
3050 1.35E-08 2.57E-07 6.64 5.03 20 44 Proteasome
5010 3.60E-08 6.16E-07 2.99 18.32 43 160 Alzheimer's disease
4012 4.15E-08 6.46E-07 4.01 9.96 29 87 ErbB signaling pathway
4930 5.38E-08 7.66E-07 5.89 5.38 20 47 Type II diabetes mellitus
5200 7.16E-08 8.98E-07 2.25 37.56 70 328 Pathways in cancer
5215 7.35E-08 8.98E-07 3.88 10.19 29 89 Prostate cancer
5221 9.62E-08 1.10E-06 5.01 6.52 22 57 Acute myeloid leukemia
4910 2.39E-07 2.56E-06 3.02 15.57 37 136 Insulin signaling pathway
5223 8.13E-07 8.17E-06 4.67 6.18 20 54 Non-small cell lung cancer
5210 1.09E-06 1.03E-05 3.58 9.62 26 84 Colorectal cancer
5213 1.95E-06 1.76E-05 4.57 5.95 19 52 Endometrial cancer
5212 2.49E-06 2.12E-05 3.73 8.24 23 72 Pancreatic cancer
4370 5.44E-06 4.43E-05 3.52 8.59 23 75 VEGF signaling pathway
5216 6.07E-06 4.72E-05 6.40 3.32 13 29 Thyroid cancer
4150 8.84E-06 6.57E-05 4.19 5.95 18 52 mTOR signaling pathway
4912 9.98E-06 7.11E-05 2.99 11.33 27 99 GnRH signaling pathway
4540 1.50E-05 0.000102 3.06 10.30 25 90 Gap junction
5222 2.05E-05 0.000134 3.08 9.85 24 86 Small cell lung cancer
4062 2.89E-05 0.000183 2.23 21.64 41 189 Chemokine signaling pathway
4010 3.57E-05 0.000217 1.98 30.81 53 269 MAPK signaling pathway
4510 5.21E-05 0.000306 2.13 22.90 42 200 Focal adhesion
5020 6.86E-05 0.000391 4.65 4.00 13 35 Prion diseases
4620 0.000103093 0.000568 2.64 11.45 25 100 Toll-like receptor signaling pathway
4666 0.000118526 0.000614 2.68 10.88 24 95 Fc gamma R-mediated phagocytosis
4920 0.000117331 0.000614 3.13 7.67 19 67 Adipocytokine signaling pathway
5120 0.000145802 0.000733 3.06 7.78 19 68 Epithelial cell signaling in Helicobacter pylori infection
5220 0.000162096 0.000791 2.93 8.47 20 74 Chronic myeloid leukemia
4662 0.000197904 0.000940 2.87 8.59 20 75 B cell receptor signaling pathway
5211 0.000221463 0.001023 2.94 8.01 19 70 Renal cell carcinoma
4730 0.000270799 0.001218 2.88 8.13 19 71 Long-term depression
4664 0.000290876 0.001275 2.77 8.81 20 77 Fc epsilon RI signaling pathway
4144 0.000364952 0.001560 2.01 21.07 37 184 Endocytosis
5214 0.000507164 0.002115 2.91 7.21 17 63 Glioma
5012 0.000552313 0.002248 2.23 14.08 27 123 Parkinson's disease
4310 0.000750976 0.002986 2.05 17.29 31 151 Wnt signaling pathway
4660 0.000920987 0.003579 2.26 12.37 24 108 T cell receptor signaling pathway
4270 0.001574869 0.005984 2.15 12.82 24 112 Vascular smooth muscle contraction
1063 0.002467529 0.009172 2.61 6.87 15 60 Biosynthesis of alkaloids derived from shikimate pathway
5110 0.002843628 0.010345 2.68 6.29 14 55 Vibrio cholerae infection
1062 0.002972209 0.010588 2.46 7.67 16 67 Biosynthesis of terpenoids and steroids
4070 0.00345029 0.012040 2.34 8.47 17 74 Phosphatidylinositol signaling system
380 0.00415394 0.014206 2.97 4.58 11 40 Tryptophan metabolism
1061 0.004793014 0.016070 2.49 6.64 14 58 Biosynthesis of phenylpropanoids
5218 0.005483501 0.018032 2.28 8.13 16 71 Melanoma
1066 0.006325703 0.020031 2.24 8.24 16 72 Biosynthesis of alkaloids derived from terpenoid and polyketide
5219 0.006221175 0.020031 2.77 4.81 11 42 Bladder cancer
1064 0.010319521 0.032084 2.23 7.21 14 63 Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid