KEGG Pathways enriched in HD-relevant genes

KEGG IDs are linked to the KEGG website (http://www.genome.jp). The list of HD-relevant genes for each category can be found following the links provided in the Term column.

KEGGID P-Value FDR Odds Ratio Expected Count Count Total number Term
03010 4.59E-14 7.35E-12 7.26 6.65 31 85 Ribosome
03050 1.40E-11 7.49E-10 10.29 3.44 20 44 Proteasome
04210 2.50E-06 7.99E-05 3.84 6.88 21 88 Apoptosis
04010 7.84E-06 0.000173 2.32 21.04 42 269 MAPK signaling pathway
04722 8.67E-06 0.000173 3.07 9.78 25 125 Neurotrophin signaling pathway
04012 0.000101 0.001473 3.17 6.80 18 87 ErbB signaling pathway
05120 0.000180 0.002227 3.42 5.32 15 68 Epithelial cell signaling in Helicobacter pylori infection
04120 0.000211 0.002418 2.55 10.40 23 133 Ubiquitin mediated proteolysis
04310 0.000230 0.002457 2.42 11.81 25 151 Wnt signaling pathway
04720 0.000254 0.002545 3.30 5.47 15 70 Long-term potentiation
04920 0.000534 0.004504 3.19 5.24 14 67 Adipocytokine signaling pathway
04540 0.001421 0.009886 2.61 7.04 16 90 Gap junction
04620 0.001699 0.010658 2.47 7.82 17 100 Toll-like receptor signaling pathway
04662 0.001721 0.010658 2.76 5.86 14 75 B cell receptor signaling pathway
01062 0.001731 0.010658 2.89 5.24 13 67 Biosynthesis of terpenoids and steroids
04150 0.001877 0.011127 3.22 4.06 11 52 mTOR signaling pathway
04020 0.002314 0.013225 2.01 13.77 25 176 Calcium signaling pathway
04510 0.003296 0.018046 1.90 15.64 27 200 Focal adhesion
01066 0.003383 0.018046 2.65 5.63 13 72 Biosynthesis of alkaloids derived from terpenoid and polyketide
04912 0.003903 0.019500 2.32 7.74 16 99 GnRH signaling pathway
04660 0.003940 0.019500 2.25 8.45 17 108 T cell receptor signaling pathway
04910 0.004143 0.019500 2.08 10.64 20 136 Insulin signaling pathway
01061 0.004627 0.021155 2.80 4.53 11 58 Biosynthesis of phenylpropanoids
01070 0.007769 0.033598 2.27 6.88 14 88 Biosynthesis of plant hormones
04730 0.008247 0.034726 2.44 5.55 12 71 Long-term depression
01064 0.008795 0.035182 2.53 4.92 11 63 Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
04370 0.012681 0.049487 2.28 5.86 12 75 VEGF signaling pathway
04666 0.014980 0.056326 2.07 7.43 14 95 Fc gamma R-mediated phagocytosis
04115 0.015409 0.056326 2.31 5.32 11 68 p53 signaling pathway
04664 0.015489 0.056326 2.21 6.02 12 77 Fc epsilon RI signaling pathway
04110 0.016760 0.057225 1.89 9.78 17 125 Cell cycle
01063 0.016778 0.057225 2.39 4.69 10 60 Biosynthesis of alkaloids derived from shikimate pathway
04070 0.027614 0.083364 2.08 5.78 11 74 Phosphatidylinositol signaling system
04144 0.028646 0.084878 1.63 14.39 22 184 Endocytosis
01065 0.060784 0.167681 1.86 5.78 10 74 Biosynthesis of alkaloids derived from histidine and purine
00190 0.065555 0.177776 1.61 9.85 15 126 Oxidative phosphorylation
04916 0.088751 0.236671 1.62 7.82 12 100 Melanogenesis